Abstract
Background:
Feelings of isolation, insecurity, and instability triggered by COVID-19 could have a long-term impact on the mental health status of individuals.
Objectives:
The aim of this study was to examine the prevalence of mental health symptoms (anxiety, depression, and stress) in Bangladesh and the factors associated with these symptoms during the COVID-19 pandemic.
Methods:
From 1 to 30 April 2020, we used a validated self-administered questionnaire to conduct a cross-sectional study on 10,609 participants through an online survey platform. We assessed mental health status using the Depression, Anxiety, and Stress Scale (DASS-21). The total depression, anxiety, and stress subscale scores were divided into normal, mild, moderate, severe, and multinomial logistic regression was used to examine associated factors.
Findings:
The prevalence of depressive symptoms was 15%, 34%, and 15% for mild, moderate, and severe depressive symptoms, respectively. The prevalence of anxiety symptoms was 59% for severe anxiety symptoms, 14% for moderate anxiety symptoms, and 14% for mild anxiety symptoms, while the prevalence for stress levels were 16% for severe stress level, 22% for moderate stress level, and 13% for mild stress level. Multivariate analyses revealed that the most consistent factors associated with mild, moderate, and severe of the three mental health subscales (depression, anxiety, and stress) were respondents who lived in Dhaka and Rangpur division, females, those who self-quarantined in the previous seven days before the survey, and those respondents who experienced chills, breathing difficulty, dizziness, and sore throat.
Conclusion:
Our results showed that about 64%, 87%, and 61% of the respondents in Bangladesh reported high levels of depression, anxiety, and stress, respectively. There is a need for mental health support targeting women and those who self-quarantined or lived in Dhaka and Rangpur during the pandemic.
Introduction
As the global population tries to make sense of the transformations, including personal adjustments to lifestyle, brought about by the COVID-19 pandemic, residents of low- to middle-income countries (LMIC) including Bangladesh face greater challenges due to the fragile health systems [1,2], the dense population of Bangladesh, and the fact that the country houses a million stateless Rohingya refugees in sprawling refugee camps that are conducive to the spread of epidemics. Bangladesh also has significant migrant populations living in Italy, a COVID-affected country [1]. Whilst the mortality rates in Bangladesh have remained low, due to the timing of the infection, the early transmission of the virus, and the response to the pandemic by authorities, the low socio-economic status of the country and the existing health inequalities usually lead to worse effects [3].
Science has played a significant role in improving people’s understanding of the virus, finding effective ways of containment through timely sequencing of the virus and rapid sharing of the data [4], and most recently the development of different vaccines. Unraveling the genetic sequence of the SARS-COV-2 virus about four weeks after the outbreak of the SARS-COV-2 virus [5] was short compared to the Spanish flu, which took almost seven decades for scientists to unravel the genetic sequence of the disease [6], and was crucial to the development of a diagnostic test and potential treatment [7,8]. Globally, the virus has infected over 84 million people, including 1.8 million reported deaths from the infection at the time of this study. In Bangladesh, there have been 515,000 confirmed cases as of 2 January 2021, with 7,576 deaths reported to the World Health Organization (WHO) [9]. The COVID-19 pandemic spread faster, and the mortality rate is higher, than those attributed to the Middle Eastern respiratory syndrome (MERS) and Severe acute respiratory syndrome (SARS). Thus, there was fear and panic among residents as news about its fatal nature spread very easily through traditional and social media outlets, leaving behind a trail of despair and disruptions in lifestyle. The high mortality rate, closure of businesses, and strict containment measures by national governments also added to the hidden and unhidden mental health burden of the pandemic [10,11]. However, no one has been able to report comprehensively the mental health impact of the pandemic in most LMIC.
Despite the delay in COVID-19 cases in Bangladesh (the first case was reported 18 March 2020), the country’s global supply chain of international fashion brands and human resource exports suffered a huge set-back with devastating psychosocial consequences emanating from the international and local economic impacts [12]. Post-traumatic stress symptoms, as well as delayed grief and the sense of loss, after multiple deaths and loss of jobs and avenues to socialize have been reported in previous studies [13].
The burden of mental disorders is already high in Bangladesh, and this is a largely unrecognized and under-researched area in Bangladesh as shown in a review study [14]. In addition to the mental health burden from displaced Rohingya refugees [15], the outbreak of COVID-19 may have an additional negative impact on the state of mental health in Bangladesh. In a web-based cross-sectional study conducted in the US using electronic Qualtrics software, female college students reported higher levels of perceived stress and inability to focus on their academic work during the COVID-19 pandemic [16]. Similarly, in a web-based observational study conducted in Italy, which evaluated the impact of the COVID-19 pandemic on infertile couples’ emotions, anxiety, and future plans, the authors used the Survey Monkey platform and the web link of the survey was sent via emails and published on six online forums frequented by infertile patients. The couples undergoing assisted reproductive treatment showed severe psychological impact of the COVID-19 pandemic, particularly among women who were more emotionally distressed, anxious, and depressed than their men counterparts. This was because assisted reproductive treatment was stopped in many centres due to rising concern as to the impact of COVID-19 on pregnancy [17]. Coupled with these are the uncertainties about effective treatment, availability of effective vaccines, as well as whether life could return to normal.
All these could negatively affect the mental health of the populace and, by extension, the productivity of the country that depends largely on international trading, which has so far been decimated by the pandemic. Health care delivery in Bangladesh has major challenges, including weak governance and an over-centralized framework, the poorly regulated private sector that employs over 58% of all physicians work in the poorly regulated private sector, and the lack of funding for the public sector [18]. Layered on top of these are the lack of resources and the disproportionate distribution of mental health services in Bangladesh, leading to poor access to mental health facilities and care [19]. Therefore, the aim of this study was to determine the prevalence of mental health symptoms during the pandemic and to identify the factors associated with the mental health symptoms in a Bangladesh population. The findings of this study will provide meaningful supplementary and complementary data to inform the understanding of the impact of the COVID-19 pandemic on global mental health regarding a densely populated, geopolitically and economically-critical region.
Methods
Study design and setting
A cross-sectional online study was conducted in Khulna, Chittagong, Mymensing, Rajshahi, Barisal, Rangpur, Sylhet, and Dhaka divisions in Bangladesh from April 1–30, 2020, corresponding to the mandatory lockdown period imposed in different parts of the country.
Bangladesh is a developing nation in South-East Asia that became a separate political and economic entity only 50 years ago. Originally part of the British Raj and then pre-Independence India, Bangladesh became an eastern province of Pakistan and gained independence in 1947 following its ‘Great Liberation War’ and was named Bangladesh [20]. Bangladesh covers 147,570 square kilometres and has a population of roughly163 million, with India and Myanmar at its borders and majority are Muslims (89%). About 38.2% of the population residing in urban areas, including the capital Dhaka, which has an estimated population of 21 million people and growing [21]. The country has about 220 psychiatrists and 50 trained clinical psychologists serving the whole nation [20] and has absorbed close to a million refugees from Myanmar in recent years.
Sampling
Invitations to participate were sent out online through social media platforms (e.g., Facebook, Google Plus, LinkedIn, and Twitter) because traditional face-to-face interviews were not possible due to the lockdown. The use of social media platforms also enabled the researchers to reach target respondents living in different parts of Bangladesh. Residents were also asked to share the e-link with their friends and networks to increase the reach. A snow-ball sampling technique was used for collecting information from participants.
To be eligible for participation in this study, the respondents had to reside in Bangladesh, be able to provide online informed consent, and be 18 years and over at the time of data collection. Informed consent was obtained through an online preamble before the respondents began the questionnaire. The participants were assured of the anonymity and confidentiality of their responses and information provided as well as their freedom of choice of participation. The study was approved by the Institutional Review Board of Dr. Wazed Research and Training Institute, Begum Rokeya University, Rangpur (#BRUR/DWRTI/a.n.004). All procedures were in accordance with the 1964 Helsinki Declaration of Helsinki as revised in Fortaleza.
Measurements
A web-based self-administered survey created on Google forms was distributed across Bangladesh to reach the target respondents living in different parts of Bangladesh. The respondents clicked the link on the platform and responded to the survey voluntarily. The first part of the survey obtained participants’ demographic information.
The survey was divided into five parts as shown in Table 1: The first part gathered demographic information of the participants, including gender, age, living area (division), level of education, marital status, and working status. The second part was the household factors, which asked about living arrangements and the number living together. The third part included COVID-19 factors, which asked whether/not the participants had been tested for COVID-19. The fourth part evaluated the compliance with WHO recommended precautionary measures, including avoiding crowded gatherings, handshaking and use of public transport, wearing facemasks when going out, advocating with other people about the health risks of the infection. The fifth part evaluated the history of health-related symptoms (if the respondents had experienced any symptoms—fever, pain, headache, chills persistent, dizziness, and breathing difficulties—a couple of weeks before data collection). The information about these five parts is listed in Supplementary Table 1.
Table 1.
VARIABLES | n | PERCENT (%) |
---|---|---|
Demography | ||
Division of Living | ||
Khulna | 1788 | 16.85 |
Chittagong | 1198 | 11.29 |
Mymensing | 288 | 2.71 |
Rajshahi | 674 | 6.35 |
Barisal | 716 | 6.75 |
Rangpur | 464 | 4.37 |
Sylhet | 221 | 2.08 |
Dhaka | 5260 | 49.58 |
Gender | ||
Male | 5238 | 49.37 |
Female | 5371 | 50.63 |
Level of Education | ||
Postgraduate/Post Doctorate | 2291 | 21.59 |
Graduate | 3942 | 37.16 |
HSC or Equivalent | 2881 | 27.16 |
SSC or Equivalent | 969 | 9.13 |
Under SSC | 526 | 4.96 |
Age Category | ||
18–27 years | 6043 | 56.96 |
28–37 years | 2423 | 22.84 |
38–47 years | 1157 | 10.91 |
48–57 years | 709 | 6.68 |
58+ years | 277 | 2.61 |
Marital Status | ||
Single | 4833 | 45.56 |
Married | 5332 | 50.26 |
Divorced/Widowed | 444 | 4.19 |
Working Status | ||
Working (Full time) | 4754 | 44.81 |
Working (Part-time) | 1220 | 11.50 |
Not working/Student | 4635 | 43.69 |
Household Factors | ||
Living Arrangement | ||
Living with Family | 8533 | 80.43 |
Living Alone | 1504 | 14.18 |
Sharing/Living with Flatmates | 572 | 5.39 |
Household Size | ||
1–2 People | 1281 | 12.07 |
3–4 People | 9328 | 87.93 |
Have you been tested for COVID-19? | ||
No | 9434 | 88.92 |
Yes, I Tested Negative | 832 | 7.84 |
Yes. I Tested Positive | 343 | 3.23 |
Compliance with Public health measures | ||
Have You Enforced Protective Measures Inside Your Home to Protect Yourself and Your Family from COVID 19? | ||
Yes | 9705 | 91.48 |
No | 904 | 8.52 |
Are You Currently in Self-Quarantine Since Past Seven Days? | ||
No | 2155 | 20.31 |
Yes | 8454 | 79.69 |
What Sort of Protective Measures Have You Taken? | ||
Avoid Public Transport | ||
Yes | 2230 | 21.02 |
No | 8379 | 78.98 |
Avoid Shaking Hands | ||
Yes | 2313 | 21.80 |
No | 8296 | 78.20 |
Wearing Face Mask | ||
Yes | 2368 | 22.32 |
No | 8241 | 77.68 |
Avoid Large Gatherings | ||
Yes | 2352 | 22.17 |
No | 8257 | 77.83 |
Advocating People About the Health Risk Related to COVID-19 | ||
Yes | 1792 | 16.89 |
No | 8817 | 83.11 |
Responses Regarding the Health Condition for the Last Couple of Weeks | ||
Fever For at least A Day | ||
No | 9179 | 86.52 |
Yes | 1430 | 13.48 |
Chills For at least a Day | ||
No | 9225 | 86.95 |
Yes | 1384 | 13.05 |
Headache For at least a day | ||
No | 7851 | 74.00 |
Yes | 2758 | 26.00 |
Cough For at least a Day | ||
No | 8228 | 77.56 |
Yes | 2381 | 22.44 |
Breathing Difficulty | ||
No | 9207 | 86.78 |
Yes | 1402 | 13.22 |
Dizziness | ||
No | 8802 | 82.97 |
Yes | 1807 | 17.03 |
Sore Throat | ||
No | 8761 | 82.58 |
Yes | 1848 | 17.42 |
Persistent fever and cough or difficulty in breathing | ||
No | 9727 | 91.69 |
Yes | 882 | 8.31 |
Outcome Measures
The mental health symptoms of depression, anxiety, and stress were the outcome measures. The Depression, Anxiety and Stress Scale-21 Items (DASS-21) is a set of three self-report scales designed to measure the emotional states of depression, anxiety, and stress and were calculated based on a previous study [22]. These instruments are often used to assess subjective complaints and do not directly imply that respondents have a discrete diagnosis as classified in the diagnostic and statistical manual of mental disorders (DSM) and international classification of diseases and related health problems (ICD) [23]. However, their use in this study was predominantly aimed at assessing the perceived severity of symptoms related to depression, anxiety, and stress [24].
Depression subscale
Responses to each item were rated from 0 (never) to 3 (almost always). Items 3, 5, 10, 13, 16, 17, and 21 (see supplementary Table 1) were classified as the depression subscale, and the total depression subscale score was multiplied by 2 to calculate the final score and then divided into normal (0–9), mild depression (10–13), moderate depression (14–20), severe depression (21+). The validity of the tool was tested, and the Cronbach’s alpha coefficient ranged from 0.75 to 0.77 among the depression subscale, indicating a satisfactory level of reliability.
Anxiety subscale
Items 2, 4, 7, 9, 15, 19, and 20 (see supplementary Table 1) formed the anxiety subscale, and the total anxiety subscale score was multiplied by 2 to calculate the final score and then divided into normal (0–7), mild anxiety (8–9), moderate anxiety (10–14), severe anxiety (15+) [18]. The Cronbach’s alpha coefficient testing the validity of the anxiety subscale showed scores ranging from 0.65 to 0.77, indicating acceptable internal consistency.
Stress subscale
Items 1, 6, 8, 11, 12, 14, and 18 (see supplementary Table 1) were classified as the stress subscale. The total stress subscale score was multiplied by 2 to calculate the final score and then divided into normal (0–14), mild stress (15–18), moderate stress (19–25), severe stress (26+), and extremely severe stress (35–42) [22]. The Cronbach’s alpha coefficient of stress subscale scores ranged from 0.78 to 0.81, indicating an acceptable level of internal consistency.
Data Analysis
Statistical analysis
Data were analysed using the STATA/MP Version.14.1 (Stata Corp 2015, College Station, TX, USA). Descriptive statistics using frequency tabulations were used to present the sample characteristics. The prevalence and 95% confidence intervals (CIs) for normal, mild, moderate, and severe levels of depression, anxiety, and stress were calculated. The association was further tested by odds ratios (OR) using univariate and multiple multinomial logistic regression analyses to identify factors associated with symptoms of depression, anxiety, and levels of stress. In the multiple multinomial logistic regression analyses, four-stage modeling was employed. In the first stage, the demographic factors were entered into the model. We conducted a manually executed elimination method to determine factors associated with symptoms of depression, anxiety, and levels of stress. The significant factors in the first stage were added to the household factors in the second stage model; this was then followed by the elimination procedure. We used a similar statistical approach for compliance with public health and health condition/factors in the third and fourth stages, respectively. Associations were presented as unadjusted OR for all explanatory variables and then adjusted OR (AOR) with their 95% CI for the variables retained in the final step. The level of statistical significance was set at p < 0.05.
Spatial analysis
We conducted spatial distribution for the three mental health subscales. A series of maps were prepared using ArcGIS Desktop 10.8 [25]. The average level of depression, anxiety, and stress for the first-level administrative unit of Bangladesh (division) was calculated based on the identification of factors through map comparisons and regression analysis for mild, moderate, and severe levels of the mental health variables. In the maps, the adjusted odds ratios (AOR) for each level was categorized into five quantiles and presented using graduated colour symbols.
Results
Sociodemographic characteristics of the study sample
Table 1 shows the study sample characteristics. Of the 10,900 participants who completed the questionnaire, data for 10,660 adult respondents from the 8 divisions in Bangladesh who provided responses for the outcome measures of interest were included in the analysis. There were 5,238 males (49.1%), mostly young (18–37 years: 8,466, 79.4%), married people (5,332, 50.3%), who had a university degree or higher (6,233, 58.5%), and many lived in Dhaka division (5,260, 49.6%) with their families (8,533, 80.4%) or with up to 3 people (9,328, 87.9%) in a house and were working full time or part-time (5,974, 56.0%) during the pandemic.
There were also 343 individuals (3.2%) with confirmed cases of COVID-19 and 832 individuals (7.8%) who tested negative to COVID-19. Although majority of the respondents reported that they enforced measures in their homes to protect their families (9,705, 91.5%) and had quarantine experience (8,454, 79.7%), more than two thirds (~78% each) did not comply with the public health advice asking people to avoid public transport, handshaking, large gatherings, and to always wear facemasks when going out. These were put in place to contain the spread of the disease. More than two thirds of the participants had at least one symptom of COVID-19 a couple of weeks before data collection, especially persistent fever and cough (9,727, 91.7%) and difficulty breathing (9,207, 86.8%). Additional demographic and epidemic-related characteristics are presented in Table 1.
Prevalence of depression, anxiety, and stress symptoms
The prevalence and 95% CIs for the different levels of the three mental health conditions that were examined in this study are shown in Figure 1. The prevalence was higher for anxiety 86.9% (9,267 participants total, including 1,440 participants [13.5%, 95%CI, 12.4–13.7%] with mild anxiety and 6,310 participants [59.2%, 95%CI, 58.3–60.1%] with severe anxiety), followed by depression 65.0% (6,822 participants total, including 1,563 participants [14.7%, 95%CI, 14.0–15.4%] with mild depression and 1,552 participants [14.6%, 95%CI, 13.9-15.3%] with severe depression), while 50.5% (95% CI, 28.8%–29.6%) reported stress symptoms including severe stress (1,684 participants, 15.8% [95% CI, 15.1–16.5%]).
Factors associated with symptoms of depression
The results of the unadjusted analysis of demographic and COVID-19 related variables are presented in supplementary Tables 1–3, for depression, anxiety, and stress, respectively. Table 2 presents the multivariate analysis of factors associated with depression in this cohort. In the multivariable analysis, being married; having lower than a postgraduate degree; living alone or living in shared accommodation; living in the Sylhet, Dhaka, Chittagong, Rajshahi, and Rangpur divisions; or having experienced any COVID-19 related health symptoms in the couple of weeks before data collection were associated with symptoms of depression at all levels. Figure 2 presents the adjusted odds ratios for depression symptoms among the respondents by region. The map in Figure 2 indicates that significantly high odds of depression occurred in all eight regions of Bangladesh, but residents in Rangpur, Sylhet, and Chittagong (darkest brown colour) reported the highest odds of severe depression. Individuals who were tested for COVID-19 also had remarkably higher levels of mild–severe symptoms of depression compared to those that had not been tested. In addition, female participants, those who were divorced or separated, residents of Barisal or Mymensing divisions, and those who traveled by public transport displayed a higher odds of moderate–severe symptoms of depression. Individuals with confirmed COVID-19 had at least a 50% higher odds of moderate–severe depression symptoms compared to those not tested for the disease.
Table 2.
VARIABLES | MILD | MODERATE | SEVERE | |||||
---|---|---|---|---|---|---|---|---|
aOR | P VALUE | aOR | P VALUE | aOR | P VALUE | |||
Demography | ||||||||
Division of Living | ||||||||
Khulna | 1.00 | 1.00 | 1.00 | |||||
Chittagong | 2.16 (1.65, 2.81) | <0.001 | 4.38 (3.47, 5.55) | <0.001 | 6.38 (4.77, 8.56) | <0.001 | ||
Mymensing | 0.96 (0.59, 1.57) | 0.875 | 2.68 (1.86, 3.85) | <0.001 | 2.51 (1.57, 4.01) | <0.001 | ||
Rajshahi | 1.42 (1.01, 1.98) | 0.042 | 3.56 (2.74, 4.62) | <0.001 | 3.77 (2.70, 5.27) | <0.001 | ||
Barisal | 1.04 (0.77, 1.41) | 0.782 | 1.76 (1.36, 2.27) | <0.001 | 2.09 (1.50, 2.93) | <0.001 | ||
Rangpur | 1.91 (1.28, 2.86) | 0.002 | 5.07 (3.65, 7.03) | <0.001 | 5.68 (3.82, 8.45) | <0.001 | ||
Sylhet | 5.34 (2.93, 9.75) | <0.001 | 10.67 (6.05, 18.81) | <0.001 | 15.17 (8.07, 28.53) | <0.001 | ||
Dhaka | 1.85 (1.54, 2.22) | <0.001 | 2.48 (2.11, 2.93) | <0.001 | 2.88 (2.30, 3.62) | <0.001 | ||
Gender | ||||||||
Male | 1.00 | 1.00 | 1.00 | |||||
Female | 1.14 (0.99, 1.30) | 0.060 | 1.63 (1.45, 1.83) | <0.001 | 1.71 (1.47, 1.98) | <0.001 | ||
Level of Education | ||||||||
Postgraduate/Post Doctorate | 1.00 | 1.00 | 1.00 | |||||
Graduate | 1.47 (1.24, 1.75) | <0.001 | 1.64 (1.41, 1.90) | <0.001 | 1.55 (1.28, 1.88) | <0.001 | ||
HSC or Equivalent | 1.25 (1.03, 1.52) | 0.026 | 2.00 (1.70, 2.35) | <0.001 | 2.19 (1.79, 2.68) | <0.001 | ||
SSC or Equivalent | 1.53 (1.14, 2.05) | 0.005 | 3.57 (2.84, 4.48) | <0.001 | 3.22 (2.44, 4.24) | <0.001 | ||
Under SSC | 1.61 (1.14, 2.28) | 0.007 | 2.64 (1.97, 3.53) | <0.001 | 2.89 (2.04, 4.10) | <0.001 | ||
Age in category | ||||||||
18–27 years | 1.00 | 1.00 | 1.00 | |||||
28–37 years | 1.16 (0.94, 1.44) | 0.166 | 1.21 (1.02, 1.43) | 0.032 | 1.49 (1.23, 1.82) | <0.001 | ||
38–47 years | 0.84 (0.63, 1.13) | 0.246 | 1.10 (0.89, 1.37) | 0.367 | 0.80 (0.61, 1.04) | 0.090 | ||
48–57 years | 1.90 (1.40, 2.58) | <0.001 | 1.18 (0.91, 1.52) | 0.206 | 1.03 (0.76, 1.39) | 0.848 | ||
58+ years | 0.35 (0.19, 0.65) | 0.001 | 0.96 (0.68, 1.37) | 0.828 | 0.80 (0.52, 1.25) | 0.332 | ||
Marital Status | ||||||||
Single | 1.00 | 1.00 | 1.00 | |||||
Married | 0.68 (0.56, 0.84) | <0.001 | 1.42 (1.20, 1.68) | <0.001 | 1.69 (1.36, 2.10) | <0.001 | ||
Divorced/Widowed | 1.12 (0.71, 1.78) | 0.626 | 1.71 (1.15, 2.53) | 0.008 | 2.43 (1.56, 3.76) | <0.001 | ||
Working Status | ||||||||
Working (Full time) | 1.00 | 1.00 | 1.00 | |||||
Working (Part time) | 1.23 (0.97, 1.56) | 0.089 | 0.74 (0.61, 0.89) | 0.002 | 0.88 (0.71, 1.10) | 0.281 | ||
No working/Student | 0.72 (0.59, 0.89) | 0.002 | 0.40 (0.33, 0.47) | <0.001 | 0.27 (0.22, 0.34) | <0.001 | ||
Household factor | ||||||||
Living Arrangement | ||||||||
Living with Family | 1.00 | 1.00 | 1.00 | |||||
Living Alone | 1.27 (1.04, 1.54) | 0.019 | 1.91 (1.61, 2.28) | <0.001 | 2.22 (1.80, 2.74) | <0.001 | ||
Shared accommodation/Living with Flatmates | 1.34 (1.02, 1.77) | 0.039 | 1.77 (1.37, 2.29) | <0.001 | 1.68 (1.20, 2.35) | 0.002 | ||
Household Size | ||||||||
1–2 People | 1.00 | 1.00 | 1.00 | |||||
3–4 People | 0.55 (0.45, 0.78) | <0.001 | 0.72 (0.59, 0.87) | 0.001 | 0.60 (0.48, 0.75) | <0.001 | ||
Have you been tested for COVID-19? | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes, I Tested Negative | 1.85 (1.38, 2.49) | <0.001 | 2.52 (1.94, 3.26) | <0.001 | 2.24 (1.67, 3.02) | <0.001 | ||
Yes, I Tested Positive | 1.48 (0.87, 2.54) | 0.152 | 2.08 (1.31, 3.28) | 0.002 | 1.92 (1.17, 3.16) | 0.010 | ||
Compliance with Public health measures | ||||||||
Are You Currently in Self-Quarantine Since Past Seven Days? | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 0.77 (0.66, 0.91) | 0.002 | 1.41 (1.21, 1.64) | <0.001 | 1.89 (1.53, 2.33) | <0.001 | ||
Avoid Public Transport | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 0.91 (0.62, 1.33) | 0.626 | 2.57 (1.86, 3.56) | <0.001 | 2.52 (1.70, 3.73) | <0.001 | ||
Avoid Shaking Hands | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 0.69 (0.48, 1.00) | 0.051 | 1.08 (0.78, 1.48) | 0.651 | 1.76 (1.20, 2.56) | 0.003 | ||
Wearing Face Mask when going out | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 0.92 (0.66, 1.28) | 0.634 | 1.28 (0.97, 1.71) | 0.081 | 1.39 (0.99, 1.96) | 0.057 | ||
Avoid Large Gatherings | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 1.53 (1.10, 2.12) | 0.011 | 0.62 (0.46, 0.82) | 0.001 | 0.67 (0.48, 0.95) | 0.023 | ||
Advocating People About the Health Risk Related to COVID-19 | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 0.76 (0.61, 0.95) | 0.017 | 0.50 (0.41, 0.62) | <0.001 | 0.56 (0.43, 0.73) | <0.001 | ||
Health Condition experienced in the Last Week | ||||||||
Fever | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 1.25 (0.99, 1.57) | 0.051 | 0.90 (0.74, 1.10) | 0.290 | 1.37 (1.09, 1.72) | 0.006 | ||
Chills | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 1.32 (1.01, 1.72) | 0.041 | 2.05 (1.65, 2.56) | <0.001 | 2.19 (1.72, 2.78) | <0.001 | ||
Headache | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 1.15 (0.98, 1.36) | 0.089 | 1.43 (1.25, 1.64) | <0.001 | 1.13 (0.96, 1.35) | 0.144 | ||
Cough | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 2.55 (2.14, 3.03) | <0.001 | 2.45 (2.10, 2.86) | <0.001 | 1.68 (1.39, 2.02) | <0.001 | ||
Breathing Difficulty | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 3.29 (2.48, 4.35) | <0.001 | 3.15 (2.47, 4.03) | <0.001 | 4.43 (3.41, 5.76) | <0.001 | ||
Dizziness | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 1.92 (1.53, 2.40) | <0.001 | 2.42 (1.99, 2.93) | <0.001 | 1.86 (1.49, 2.32) | 0.001 | ||
Sore Throat | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 1.84 (1.48, 2.27) | <0.001 | 2.26 (1.89, 2.70) | <0.001 | 2.15 (1.75, 2.65) | <0.001 | ||
Adjusted odd ratios (aOR); 95% confidence intervals (CI).
Factors associated with symptoms of anxiety
Table 3 presents the multivariate analysis of factors associated with anxiety. Females, those who were divorced or widowed, those who lived in shared accommodation during the lockdown, individuals who experienced self-quarantine, and those who experienced fever and cough a couple of weeks before data collection were more likely to experience mild-severe symptoms of anxiety, while older participants experienced a lower risk of anxiety at all levels. The distribution by region (Figure 3) revealed greater than a threefold increase in the odds of feeling severely anxious among respondents residing in four regions. Compared to those from Khulna division, participants who lived in other divisions, particularly Chittagong [aOR, 6.26, 95%CI, 4.40–8.90], Mymensing [aOR 5.26, 95%CI, 3.04–9.12], and Rangpur [aOR, 5.86, 95%CI, 3.64–9.42] were more likely to feel severely anxious (see Figure 3) as well as those who lived alone [aOR, 1.70, 95%CI, 1.35–2.16] during the lockdown. Those with confirmed or suspected cases of COVID-19 were about two times more likely to experience severe symptoms of anxiety compared to those who were not tested. Other symptoms of COVID-19 were also significantly associated with some degree of anxiety in this study.
Table 3.
VARIABLES | MILD | MODERATE | SEVERE | |||||
---|---|---|---|---|---|---|---|---|
aOR | P-VALUE | aOR | P-VALUE | aOR | P-VALUE | |||
Demography | ||||||||
Division of Living | ||||||||
Khulna | 1.00 | 1.00 | 1.00 | |||||
Chittagong | 1.38 (0.91, 2.09) | 0.124 | 3.28 (2.23, 4.83) | <0.001 | 6.26 (4.40, 8.90) | <0.001 | ||
Mymensing | 1.57 (0.84, 2.92) | 0.159 | 2.30 (1.24, 4.26) | 0.008 | 5.26 (3.04, 9.12) | <0.001 | ||
Rajshahi | 0.65 (0.44, 0.95) | 0.026 | 1.11 (0.77, 1.60) | 0.582 | 2.26 (1.68, 3.04) | <0.001 | ||
Barisal | 1.25 (0.92, 1.69) | 0.149 | 1.07 (0.76, 1.50) | 0.697 | 1.60 (1.21, 2.11) | 0.001 | ||
Rangpur | 1.19 (0.67, 2.11) | 0.561 | 2.17 (1.26, 3.75) | 0.005 | 5.86 (3.64, 9.42) | <0.001 | ||
Sylhet | 3.32 (0.38, 28.84) | 0.277 | 20.25 (2.71, 151.42) | <0.001 | 38.54 (5.30, 280.02) | <0.001 | ||
Dhaka | 1.13 (0.93, 1.38) | 0.233 | 1.70 (1.38, 2.09) | <0.001 | 2.91 (2.44, 3.47) | <0.001 | ||
Gender | ||||||||
Male | 1.00 | 1.00 | 1.00 | |||||
Female | 1.20 (1.01, 1.43) | 0.039 | 1.53 (1.29, 1.82) | <0.001 | 1.91 (1.65, 2.21) | <0.001 | ||
Level of Education | ||||||||
Postgraduate/Post Doctorate | 1.00 | 1.00 | 1.00 | |||||
Graduate | 1.10 (0.89, 1.36) | 0.363 | 1.19 (0.97, 1.47) | <0.001 | 1.51 (1.26, 1.81) | <0.001 | ||
HSC or Equivalent | 0.75 (0.59, 0.95) | 0.016 | 1.06 (0.84, 1.34) | 0.608 | 1.78 (1.46, 2.16) | <0.001 | ||
SSC or Equivalent | 0.96 (0.69, 1.34) | 0.811 | 0.88 (0.62, 1.25) | 0.465 | 2.34 (1.78, 3.07) | <0.001 | ||
Under SSC | 2.13 (1.38, 3.28) | 0.001 | 1.45 (0.90, 2.33) | 0.124 | 3.37 (2.30, 4.94) | <0.001 | ||
Age in category | ||||||||
18–27 years | 1.00 | 1.00 | 1.00 | |||||
28–37 years | 0.46 (0.35, 0.60) | <0.001 | 0.60 (0.46, 0.78) | <0.001 | 0.45 (0.36, 0.56) | <0.001 | ||
38–47 years | 0.39 (0.28, 0.54) | <0.001 | 0.30 (0.21, 0.42) | <0.001 | 0.27 (0.21, 0.36) | <0.001 | ||
48–57 years | 0.19 (0.12, 0.28) | <0.001 | 0.30 (0.20, 0.44) | <0.001 | 0.31 (0.23, 0.42) | <0.001 | ||
58+ years | 0.10 (0.056, 0.18) | <0.001 | 0.17 (0.10. 0.29) | <0.001 | 0.18 (0.12, 0.26) | <0.001 | ||
Marital Status | ||||||||
Single | 1.00 | 1.00 | 1.00 | |||||
Married | 0.76 (0.58, 0.98) | 0.037 | 0.80 (0.62, 1.03) | 0.088 | 1.09 (0.88, 1.35) | 0.433 | ||
Divorced/Widowed | 4.98 (2.22, 11.13) | <0.001 | 6.38 (2.94, 13.89) | <0.001 | 6.00 (2.88, 12.50) | <0.001 | ||
Working Status | ||||||||
Working (Full time) | 1.00 | 1.00 | 1.00 | |||||
Working (Part time) | 0.90 (0.66, 1.23) | 0.505 | 0.90 (0.67, 1.23) | 0.520 | 0.79 (0.61, 1.01) | 0.058 | ||
No working/Student | 0.78 (0.61, 1.01) | 0.060 | 0.96 (0.74, 1.24) | 0.761 | 0.51 (0.41, 0.63) | <0.001 | ||
Household factor | ||||||||
Living Arrangement | ||||||||
Living with Family | 1.00 | 1.00 | 1.00 | |||||
Living Alone | 0.83 (0.62, 1.12) | 0.227 | 1.13 (0.86, 1.45) | 0.366 | 1.70 (1.35, 2.16) | <0.001 | ||
Shared accommodation/Living with Flatmates | 1.87 (1.19, 2.92) | 0.006 | 2.10 (1.34, 3.29) | 0.001 | 2.42 (1.60, 3.64) | <0.001 | ||
Household Size | ||||||||
1–2 People | 1.00 | 1.00 | 1.00 | |||||
3–4 People | 0.61 (0.42, 0.88) | 0.008 | 0.63 (0.45, 0.90) | 0.011 | 0.37 (0.27, 0.50) | <0.001 | ||
Have you been tested for COVID-19? | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes, I Tested Negative | 1.02 (0.65, 1.61) | 0.932 | 1.38 (0.92, 2.07) | 0.120 | 1.85 (1.31, 2.63) | 0.001 | ||
Yes, I Tested Positive | 1.45 (0.56, 3.74) | 0.439 | 2.44 (1.05, 5.68) | 0.038 | 2.31 (1.05, 5.09) | 0.038 | ||
Compliance with Public health measures | ||||||||
Are You Currently in Self-Quarantine Since Past Seven Days? | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 2.27 (1.81, 2.86) | <0.001 | 1.53 (1.23, 1.89) | <0.001 | 1.44 (1.20, 1.73) | <0.001 | ||
Avoid Public Transport | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 0.40 (0.21, 0.74) | 0.004 | 0.74 (0.42, 1.32) | 0.306 | 1.49 (0.88, 2.52) | 0.135 | ||
Avoid Shaking Hands | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 0.52 (0.28, 0.94) | 0.030 | 0.48 (0.28, 0.85) | 0.011 | 0.81 (0.49, 1.34) | 0.411 | ||
Wearing Face Mask when going out | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 2.34 (1.40, 3.94) | 0.001 | 1.15 (0.71, 1.87) | 0.574 | 1.82 (1.17, 2.81) | 0.007 | ||
Avoid Large Gatherings | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 1.20 (0.70, 2.05) | 0.500 | 0.94 (0.57, 1.56) | 0.819 | 0.48 (0.30, 0.76) | 0.002 | ||
Advocating People About the Health Risk Related to COVID-19 | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 0.62 (0.43, 0.89) | 0.009 | 0.58 (0.42, 0.83) | 0.003 | 0.36 (0.26, 0.50) | <0.001 | ||
Health Condition experienced in the Last Week | ||||||||
Fever | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 2.07 (1.35, 3.17) | 0.001 | 1.92 (1.27, 2.89) | 0.002 | 2.80 (1.92, 4.08) | <0.001 | ||
Chills | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 1.32 (0.78, 2.25) | 0.299 | 2.75 (1.74, 4.35) | <0.001 | 4.63 (3.05, 7.02) | <0.001 | ||
Headache | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 2.54 (1.98, 3.27) | <0.001 | 2.43 (1.90, 3.10) | <0.001 | 2.17 (1.74, 2.69) | 0.144 | ||
Cough | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 2.17 (1.62, 2.90) | <0.001 | 2.51 (1.90, 3.31) | <0.001 | 2.81 (2.18, 3.63) | <0.001 | ||
Breathing Difficulty | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 0.63 (0.41, 0.97) | 0.038 | 1.03 (0.71, 1.50) | 0.878 | 1.67 (1.21, 3.30) | 0.002 | ||
Dizziness | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 0.88 (0.63, 1.23) | 0.458 | 1.21 (0.89, 1.65) | 0.215 | 1.21 (0.92, 1.59) | 0.170 | ||
Sore Throat | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 0.86 (0.60, 1.22) | 0.390 | 2.13 (1.57, 2.91) | <0.001 | 1.88 (1.42, 2.49) | <0.001 | ||
Adjusted odd ratios (aOR); 95% confidence intervals (CI).
Factors associated with symptoms of stress
The factors associated with stress in the multivariate analysis are shown in Table 4, while the regional distribution is shown in Figure 4. Those who lived in Dhaka, Rangpur, and Silhet experienced severe levels of stress during the pandemic (Figure 4). Females, those living outside of Khulna division, participants with lower than postgraduate education, those older than 27years, were married, lived alone, and had experienced self-quarantine and any of the health symptoms in this study (except for fever), were more likely to experience symptoms of stress at all levels. Participants who were divorced/widowed [aOR, 1.54, 95%CI, 1.06–2.24], those who lived in shared accommodations [aOR, 2.26, 95%CI, 1.69–3.02], as well as individuals who failed to comply with the precautionary measures advising people to avoid traveling by public transport and/or shake hands had a remarkably higher odds of moderate (aOR, 4.02, 95%CI, 2.74–5.91) and severe stress symptoms (aOR, 1.63, 95%CI, 1.15–2.30], while severe stress symptoms were also found among those who failed to wear face masks when going out [aOR, 1.64, 95%CI, 1.19–2.25].
Table 4.
VARIABLES | MILD | MODERATE | SEVERE | |||||
---|---|---|---|---|---|---|---|---|
aOR | P-VALUE | aOR | P-VALUE | aOR | P-VALUE | |||
Demography | ||||||||
Division of Living | ||||||||
Khulna | 1.00 | 1.00 | 1.00 | |||||
Chittagong | 2.10 (1.61, 2.74) | <0.001 | 3.70 (2.92, 4.68) | <0.001 | 2.87 (2.17, 3.78) | <0.001 | ||
Mymensing | 2.18 (1.44, 3.29) | <0.001 | 2.10 (1.44, 3.08) | <0.001 | 1.85 (1.18, 2.89) | 0.007 | ||
Rajshahi | 3.16 (2.36, 4.23) | <0.001 | 2.72 (2.05, 3.60) | <0.001 | 2.98 (2.18, 4.06) | <0.001 | ||
Barisal | 1.25 (0.91, 1.71) | 0.168 | 1.82 (1.38, 2.39) | <0.001 | 1.36 (0.97, 1.89) | 0.074 | ||
Rangpur | 2.51 (1.76, 3.58) | <0.001 | 3.73 (2.723, 5.11 | <0.001 | 3.21 (2.23, 4.61) | <0.001 | ||
Sylhet | 2.86 (1.81, 4.52) | <0.001 | 2.71 (1.72, 4.37) | <0.001 | 3.77 (2.32, 6.13) | <0.001 | ||
Dhaka | 1.82 (1.49, 2.23) | <0.001 | 2.42 (2.00, 2.91) | <0.001 | 3.07 (2.48, 3.80) | <0.001 | ||
Gender | ||||||||
Male | 1.00 | 1.00 | 1.00 | |||||
Female | 1.62 (1.42, 1.87) | <0.001 | 1.54 (1.37, 1.74) | <0.001 | 1.82 (1.58, 2.09) | <0.001 | ||
Level of Education | ||||||||
Postgraduate/Post Doctorate | 1.00 | 1.00 | 1.00 | |||||
Graduate | 1.85 (1.54, 2.22) | <0.001 | 2.11 (1.80, 2.47) | <0.001 | 1.89 (1.58, 2.27) | <0.001 | ||
HSC or Equivalent | 1.69 (1.38, 2.06) | <0.001 | 1.92 (1.62, 2.28) | <0.001 | 1.98 (1.64, 2.39) | <0.001 | ||
SSC or Equivalent | 2.61 (2.02, 3.37) | <0.001 | 2.56 (2.03, 3.22) | <0.001 | 3.09 (2.41, 3.94) | <0.001 | ||
Under SSC | 1.72 (1.24, 2.40) | 0.001 | 1.61 (1.20, 2.17) | 0.002 | 2.43 (1.79, 3.30) | <0.001 | ||
Age in category | ||||||||
18–27 years | 1.00 | 1.00 | 1.00 | |||||
28–37 years | 1.72 (1.42, 2.09) | <0.001 | 1.49 (1.27, 1.76) | <0.001 | 1.61 (1.35, 1.92) | <0.001 | ||
38–47 years | 1.96 (1.54, 2.50) | <0.001 | 1.49 (1.21, 1.84) | <0.001 | 1.42 (1.13, 1.80) | 0.003 | ||
48–57 years | 1.16 (0.85, 1.60) | 0.345 | 1.15 (0.89, 1.49) | 0.275 | 1..95 (1.51, 2.51) | <0.001 | ||
58+ years | 5.31 (3.63, 7.76) | <0.001 | 2.25 (1.53, 3.33) | <0.001 | 2.83 (1.87, 4.28) | <0.001 | ||
Marital Status | ||||||||
Single | 1.00 | 1.00 | 1.00 | |||||
Married | 1.72 (1.41, 2.11) | <0.001 | 1.43 (1.20, 1.71) | <0.001 | 2.05 (1.67, 2.51) | <0.001 | ||
Divorced/Widowed | 1.97 (1.38, 2.82) | <0.001 | 1.31 (0.94, 1.83) | 0.106 | 1.54 (1.06, 2.24) | 0.024 | ||
Working Status | ||||||||
Working (Full time) | 1.00 | 1.00 | 1.00 | |||||
Working (Part time) | 1.11 (0.90, 1.38) | 0.329 | 0.91 (0.76, 1.10) | 0.324 | 0.68 (0.56, 0.84) | <0.001 | ||
No working/Student | 0.96 (0.79, 1.17) | 0.714 | 0.36 (0.31, 0.43) | <0.001 | 0.27 (0.22, 0.34) | <0.001 | ||
Household factor | ||||||||
Living Arrangement | ||||||||
Living with Family | 1.00 | 1.00 | 1.00 | |||||
Living Alone | 1.60 (1.33, 1.93) | <0.001 | 1.67 (1.41, 1.98) | <0.001 | 1.71 (1.40, 2.08) | <0.001 | ||
Shared accommodation/Living with Flatmates | 1.02 (0.75, 1.40) | 0.883 | 1.59 (1.23, 2.06) | <0.001 | 2.26 (1.69, 3.02) | <0.001 | ||
Household Size | ||||||||
1–2 People | 1.00 | 1.00 | 1.00 | |||||
3–4 People | 0.76 (0.62, 0.93) | 0.007 | 0.74 (0.61, 0.88) | 0.001 | 0.58 (0.47, 0.70) | <0.001 | ||
Have you been tested for COVID-19? | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes, I Tested Negative | 1.57 (1.23, 2.01) | <0.001 | 1.77 (1.42, 2.21) | <0.001 | 1.22 (0.94, 1.57) | 0.136 | ||
Yes, I Tested Positive | 1.38 (0.95, 2.01) | 0.095 | 1.42 (1.01, 1.99) | 0.046 | 1.10 (0.75, 1.60) | 0.636 | ||
Compliance with Public health measures | ||||||||
Have You Enforced Protective Measures Inside Your Home to Protect Yourself and Your Family from COVID 19? | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 1.08 (0.85, 1.38) | 0.540 | 1.18 (0.94, 1.47) | 0.148 | 1.28 (1.00, 1.65) | 0.049 | ||
Are You Currently in Self-Quarantine Since Past Seven Days? | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 1.28 (1.07, 1.53) | 0.007 | 2.09 (1.75, 2.49) | <0.001 | 1.92 (1.55, 2.38) | <0.001 | ||
Avoid Public Transport | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 1.08 (0.80, 1.47) | 0.601 | 1.60 (1.20, 2.13) | 0.001 | 4.02 (2.74, 5.91) | <0.001 | ||
Avoid Shaking Hands | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 0.94 (0.70, 1.27) | 0.700 | 0.68 (0.52, 0.90) | 0.007 | 1.63 (1.15, 2.30) | 0.006 | ||
Wearing Face Mask when going out | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 1.25 (0.95, 1.64) | 0.107 | 1.15 (0.89, 1.48) | 0.291 | 1.64 (1.19, 2.25) | 0.002 | ||
Avoid Large Gatherings | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 1.12 (0.86, 1.47) | 0.398 | 1.72 (1.35, 2.19) | <0.001 | 1.18 (0.88, 1.58) | 0.257 | ||
Advocating People About the Health Risk Related to COVID-19 | ||||||||
Yes | 1.00 | 1.00 | 1.00 | |||||
No | 0.55 (0.45, 0.68) | <0.001 | 0.99 (0.81, 1.21) | 0.916 | 0.66 (0.51, 0.84) | 0.001 | ||
Health Condition experienced in the Last Week | ||||||||
Fever | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 0.96 (0.78, 1.17) | 0.663 | 1.11 (0.93, 1.32) | 0.252 | 1.07 (0.88, 1.31) | 0.509 | ||
Chills | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 1.99 (1.62, 2.44) | <0.001 | 2.07 (1.72, 2.49) | <0.001 | 2.01 (1.65, 2.46) | <0.001 | ||
Headache | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 1.26 (1.08, 1.48) | 0.004 | 1.63 (1.42, 1.86) | <0.001 | 1.50 (1.29, 1.75) | <0.001 | ||
Cough | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 1.27 (1.08, 1.50) | 0.004 | 1.79 (1.56, 2.07) | <0.001 | 1.32 (1.12, 1.55) | 0.001 | ||
Breathing Difficulty | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 2.14 (1.74, 2.62) | <0.001 | 1.73 (1.44, 2.08) | <0.001 | 2.18 (1.79, 2.66) | <0.001 | ||
Dizziness | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 1.45 (1.20, 1.76) | <0.001 | 1.91 (1.63, 2.25) | <0.001 | 1.50 (1.25, 1.80) | <0.001 | ||
Sore Throat | ||||||||
No | 1.00 | 1.00 | 1.00 | |||||
Yes | 1.33 (1.11, 1.60) | 0.002 | 1.38 (1.18, 1.61) | <0.001 | 1.39 (1.16, 1.66) | <0.001 | ||
Adjusted odd ratios (aOR); 95% confidence intervals (CI).
Discussion
This cross-sectional survey used an online survey to assess the prevalence and associated factors of mental health symptoms related to the COVID-19 pandemic in Bangladesh. The study utilized internationally recognized scales and found a high prevalence of mental health symptoms during the pandemic, particularly feeling anxious and depressed, and about half of the respondents experienced stress. Respondents who reported these mental health symptoms during the pandemic were more likely to be females, be married, have lower education, face various factors related to accommodation and living arrangements, and experience COVID-19 related health symptoms. In addition, respondents who were tested for COVID-19, those who traveled via public transport, and people who practiced self-quarantine self-reported a higher prevalence of depression, anxiety, and stress in this study.
In this study, the prevalence of mental health symptoms was higher than previous reports from the United Kingdom [26] and Iran [27] during the COVID-19 pandemic further confirming the high burden of the disease in this region [14]. Similar high prevalence of depression, anxiety, and psychological distress have been reported in other countries during a pandemic including Ethiopia [28] and Australia, particularly during the highly infectious equine influenza in 2007 [29]. Although the higher prevalence of mental health symptoms found in this study may be related to the methods used in assessing the mental health symptoms, it is an indication of an unmet need in the country’s health care system that is fueled by the pandemic and lack of psychiatrists to fulfil these needs [30].
Previous epidemiological studies reported that women were at a higher risk of depression [31] than men and were more vulnerable to stress and post-traumatic stress disorder than men [32]. These findings were corroborated in recent studies where the prevalence of anxiety, depression, and stress during the COVID-19 pandemic was significantly higher among women than men [33,34,35]. Compared with the previous studies, the present study used a larger sample size to confirm that women in Bangladesh experienced significantly higher mental health symptoms than men, and this could be due to the higher representation of women in various industries like retail, manufacturing, healthcare, and service, which were affected by the current pandemic. With the uneven effects in the employment sector, there are suggestions that women were more likely to experience psychological and mental health problems when faced with depression, anxiety, and stress [36].
Older people had a higher risk of COVID-19 infection and mortality [37]; however, the results of existing studies found higher levels of anxiety, depression, and stress among the younger population, particularly those aged 21–40 years [11,38]. That age was associated with the participants’ report of depression, anxiety, and stress in this study may be attributed to the fact that people in this age group are more concerned over the future consequences and economic challenges caused by the pandemic, as they are the key actors in society’s workforce and are, therefore, mostly affected by fear of joblessness and business closures [39]. Some researchers have argued that greater anxiety among young people may be related to their greater access to information through social media, which can also cause severe stress [40,41]. And people become stressed and feel anxious when information from public health experts is unreliable or delivered incorrectly and as such could create confusion regarding the practice of self-quarantine or other public health measures put in place to control the spread of a pandemic [42].
This study found a significant association between level of education and mental health symptoms during the pandemic, which was consistent with the reports of worse mental status among the higher socio-economic class in Bangladesh [43] and among educated adolescents living in urban Dhaka [44]. Similarly, a study conducted in China at the initial stage of the COVID-19 outbreak [45] found that those with no formal education were more likely to report depression during the epidemic. Other studies have also reported significant associations between lower level of education and anxiety and depression levels [26,28]. In contrast to these studies, we found that during the COVID-19 pandemic, respondents in Bangladesh who had a higher level of education reported higher levels of anxiety, depression, and stress [35,46]: 59.75% of respondents of our study had a university level of education in comparison to respondents of the previous studies. Even some recent studies revealed similar findings to our study [47].
Similar to the findings of the present study, some authors in China [45,48] reported higher levels of anxiety among participants who had at least one family member, relative, or friend with COVID-19. That more than two thirds of the participants had at least one symptom of COVID-19 in the weeks preceding data collection and some tested positive to the virus may have contributed to the heightened prevalence of mental health symptoms reported in this study. Similar to a study in the USA [49], we found that being separated or widowed/divorced increased the likelihood of the respondents experiencing symptoms of depression during the pandemic.
During the early outbreak of COVID-19 in Bangladesh, people who came into contact with the infection were asked to isolate themselves at home or in a dedicated quarantine facility [1]. These isolation and quarantine measures increased the likelihood of mental health symptoms as more than two thirds of the study participants who practiced these measures reported mental health issues. Such negative psychological effects of the preventive measures have been reported previously during the SARS outbreak, with an increase in the levels of post-traumatic stress symptoms, confusion, and anger among residents [41]. Other studies found that self-quarantine and isolation measures, as well as employment uncertainty and the rapid spread of COVID-19 related misinformation were associated with peoples experience of psychological problems during the pandemic [40,50,51]. Due to self-quarantine measures and fear related to the spread of COVID-19, other persistent mental health disorders like anxiety, emotional disruption, and exhaustion, depression, anger, irritability, insomnia, and stress can be developed among the population [52]. Moreover, the longer the quarantine or self-isolation, the more detrimental these outcomes can become [53].
Limitations and strengths
This study had some limitations. First, it was limited in scope. Many of the participants (50%) were from the capital city of Dhaka division, limiting the generalization of our findings to rural regions. Second, the study was carried out during the COVID-19 lockdown period and lacked longitudinal follow-up. The analysis of the periodic state of individuals may not reflect the psychological state, which changes with time and with alterations in one’s surrounding environment. Because of the increasingly arduous situation and the fear of the second wave, the mental health symptoms of residents could become more severe. Thus, the long-term psychological implications of this population are worth further investigation. Third, due to ethical requirements on anonymity and confidentiality, we were not allowed to collect contact details and personal information from the respondents. As a result, we could not conduct a prospective study that would provide a concrete finding to support the need for a focused public health initiative. Fourth, the study was not able to distinguish between pre-existing mental health symptoms and new symptoms. Fifth, there was an oversampling of a particular network of peers (e.g., students), which may lead to selection bias. However, a large percentage of respondents who were within 40 years old consisted of students. They were exposed to higher mental health symptoms due to the temporary shutdown of educational institutions, disbandment of social gatherings, and pressure from having to attend classes online [54]. Sixth, the self-reported levels of psychological impact, anxiety, depression, and stress may not always align with assessment by mental health professionals.
Despite these limitations, this study has several strengths. The study provides additional global data to inform understanding of the impact of the COVID-19 pandemic in developing countries. The findings also advance the knowledge of mental health impact during the COVID-19 pandemic in such a region with a struggling health care system by providing potentially helpful data to inform possible public health management strategizing. The findings also shed added light on the impact of COVID-19 on the mental health conditions of the educated people in Bangladesh who are the potential future workforce. An impressive strength of our study is the data volume (>10,000 survey respondents), generally exceeding that of similar studies. In addition, this study used impressive GIS maps to highlight the most affected areas in Bangladesh.
Conclusions
In this survey study conducted in Bangladesh, respondents reported high rates of symptoms of depression, anxiety, and distress while non-compliance with public health measures increased the risk of mental health outcomes. Protecting the Bangladesh population is an important component of public health measures for addressing the COVID-19 pandemic. Special interventions to promote mental well-being in Bangladesh communities exposed to COVID-19 need to be immediately implemented, with women, married people, less-educated people, and those that were tested for COVID-19 requiring particular attention. To further close the gap in the relationship and improve the mental health and well-being of the Bangladeshi people, alternative ways of communication, such as the use of internet video calls [55], should be promoted during similar situations.
Data Accessibility Statement
Our data are included in the manuscript, and raw data can be released on reasonable request.
Additional Files
The additional files for this article can be found as follows:
Ethics and Consent
Ethical permission for this study was obtained from the Institutional Review Board of Dr Wazed Research and Training Institute, Begum Rokeya University, Rangpur (#BRUR/DWRTI/a.n.004), and the study adhered to the tenets of the Declaration of Helsinki as revised in Fortaleza. All the participants were informed about the specific objective of this study before proceeding to the questionnaire. Consent was obtained from all participants prior to completing the questionnaire through an online preamble. Participants were able to complete the survey only once and could terminate the survey at any time they desired. Anonymity and confidentiality of the data were ensured.
Competing Interests
The authors have no competing interests to declare.
Author Contributions
All authors had access to the data and played a role in writing the manuscript. Concept and design, all authors; acquisition, analysis, and interpretation of data, Kingsley Ago and Uchechukwu L Osuagwu; drafting of the manuscript, Christopher Piwuna, Taha Husain, Nur Yazdani, and Palash Basak; revision of the manuscript, all authors; statistical analysis, Kingsley Ago and Tanvir Abir.
Publisher’s Note
This paper underwent peer review using the Cross-Publisher COVID-19 Rapid Review Initiative.
References
- 1.Abir T, Kalimullah NA, Osuagwu UL, et al. Factors associated with the perception of risk and knowledge of contracting the SARS-Cov-2 among adults in Bangladesh: Analysis of online surveys. Int J Environ Res Public Health. 2020; 17(14): 5252. DOI: 10.3390/ijerph17145252 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2.Bong C-L, Brasher C, Chikumba E, McDougall R, Mellin-Olsen J, Enright A. The COVID-19 pandemic: Effects on low- and middle-income countries. Anesth Analg. 2020; 131(1): 86–92. DOI: 10.1213/ANE.0000000000004846 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 3.Sabawoon W. Differences by country-level income in COVID-19 cases, deaths, case-fatality rates, and rates per million population in the first five months of the pandemic. bioRxiv. Published online 2020. DOI: 10.1101/2020.07.13.20153064 [DOI] [Google Scholar]
- 4.Corman VM, Landt O, Kaiser M, et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. 2020; 25(3). DOI: 10.2807/1560-7917.ES.2020.25.3.2000045 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 5.Krammer F. SARS-CoV-2 vaccines in development. Nature. 2020; 586(7830): 516–527. DOI: 10.1038/s41586-020-2798-3 [DOI] [PubMed] [Google Scholar]
- 6.Diaz A, Marthaler D, Culhane M, Sreevatsan S, Alkhamis M, Torremorell M. Complete genome sequencing of influenza A viruses within swine farrow-to-wean farms reveals the emergence, persistence, and subsidence of diverse viral genotypes. J Virol. 2017; 91(18). DOI: 10.1128/JVI.00745-17 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 7.Alanagreh L, Alzoughool F, Atoum M. The human Coronavirus disease COVID-19: Its origin, characteristics, and insights into potential drugs and its mechanisms. Pathogens. 2020; 9(5): 331. DOI: 10.3390/pathogens9050331 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 8.Wang H, Li X, Li T, et al. The genetic sequence, origin, and diagnosis of SARS-CoV-2. Eur J Clin Microbiol Infect Dis. 2020; 39(9): 1629–1635. DOI: 10.1007/s10096-020-03899-4 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 9.WHO. Weekly operational update on COVID-19 - 30 November 2020. https://www.who.int/publications/m/item/weekly-operational-update---30-november-2020. Accessed December 27, 2020.
- 10.Ahorsu DK, Lin C-Y, Imani V, Saffari M, Griffiths MD, Pakpour AH. The fear of COVID-19 scale: Development and initial validation. Int J Ment Health Addict. Published online 2020: 1–9. DOI: 10.1007/s11469-020-00270-8 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 11.Chen B, Sun J, Feng Y. How have COVID-19 isolation policies affected young people’s mental health? - Evidence from Chinese college students. Front Psychol. 2020; 11: 1529. DOI: 10.3389/fpsyg.2020.01529 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 12.Amit S. Coronavirus and impact on the Bangladesh economy: Assessing the damage of the black swan of 2020. Asia-Pacific Journal Japan Focus. 2020; 18(15–9). [Google Scholar]
- 13.Vahdani B, Javadi SMH, Sabzi Khoshnami M, Arian M. Grief process and the COVID-19 pandemic: Wise intervention in vulnerable groups and survivors. Iran J Psychiatry Behav Sci. 2020; In Press(In Press). 103855. DOI: 10.5812/ijpbs.103855 [DOI] [Google Scholar]
- 14.Hossain MD, Ahmed HU, Chowdhury WA, Niessen LW, Alam DS. Mental disorders in Bangladesh: A systematic review. BMC Psychiatry. 2014; 14(1): 216. DOI: 10.1186/s12888-014-0216-9 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 15.Riley A, Varner A, Ventevogel P, Taimur Hasan MM, Welton-Mitchell C. Daily stressors, trauma exposure, and mental health among stateless Rohingya refugees in Bangladesh. Transcult Psychiatry. 2017; 54(3): 304–331. DOI: 10.1177/1363461517705571 [DOI] [PubMed] [Google Scholar]
- 16.Kecojevic A, Basch CH, Sullivan M, Davi NK. The impact of the COVID-19 epidemic on mental health of undergraduate students in New Jersey, cross-sectional study. PLoS One. 2020; 15(9): e0239696. DOI: 10.1371/journal.pone.0239696 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 17.Esposito V, Rania E, Lico D, et al. Influence of COVID-19 pandemic on the psychological status of infertile couples. Eur J Obstet Gynecol Reprod Biol. 2020; 253: 148–153. DOI: 10.1016/j.ejogrb.2020.08.025 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 18.WHO. https://www.who.int/workforcealliance/media/news/2012/bgd_stakeholder2012/en/. https://www.who.int/.
- 19.Nuri NN, Sarker M, Ahmed HU, Hossain MD, Beiersmann C, Jahn A. Pathways to care of patients with mental health problems in Bangladesh. Int J Ment Health Syst. 2018; 12(1). DOI: 10.1186/s13033-018-0218-y [DOI] [PMC free article] [PubMed] [Google Scholar]
- 20.Rabbani G, Ahmed HU, Desai G, Bhugra D. The Bangladesh perspective. Routledge Handbook of Psychiatry in Asia. 2015; 39. [Google Scholar]
- 21.Surhone LM, Timpledon MT, Marseken SF. The World Factbook. Betascript Publishing; 2010. [Google Scholar]
- 22.Lovibond PF, Lovibond SH. The structure of negative emotional states: Comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories. Behav Res Ther. 1995; 33(3): 335–343. DOI: 10.1016/0005-7967(94)00075-U [DOI] [PubMed] [Google Scholar]
- 23.Osman A, Wong JL, Bagge CL, Freedenthal S, Gutierrez PM, Lozano G. The Depression Anxiety Stress Scales-21 (DASS-21): Further examination of dimensions, scale reliability, and correlates: Depression anxiety stress. J Clin Psychol. 2012; 68(12): 1322–1338. DOI: 10.1002/jclp.21908 [DOI] [PubMed] [Google Scholar]
- 24.Lovibond SH, Lovibond PF. Overview of the DASS and its uses. Published online 2009. [Google Scholar]
- 25.ArcUser. Esri.com. https://www.esri.com/news/arcuser/0610/files/arcuser50/70.html. Accessed December 29, 2020.
- 26.Fancourt D, Steptoe A, Bu F. Trajectories of anxiety and depressive symptoms during enforced isolation due to COVID-19: Longitudinal analyses of 36,520 adults in England. bioRxiv. Published online 2020. DOI: 10.1101/2020.06.03.20120923 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 27.Salari N, Hosseinian-Far A, Jalali R, et al. Prevalence of stress, anxiety, depression among the general population during the COVID-19 pandemic: A systematic review and meta-analysis. Global Health. 2020; 16(1): 57. DOI: 10.1186/s12992-020-00589-w [DOI] [PMC free article] [PubMed] [Google Scholar]
- 28.Hajure M, Tariku M, Mohammedhussein M, Dule A. Depression, anxiety and associated factors among chronic medical patients amid COVID-19 pandemic in Mettu Karl Referral Hospital, Mettu, Ethiopia, 2020. Neuropsychiatr Dis Treat. 2020; 16: 2511–2518. DOI: 10.2147/NDT.S281995 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 29.Taylor MR, Agho KE, Stevens GJ, Raphael B. Factors influencing psychological distress during a disease epidemic: Data from Australia’s first outbreak of equine influenza. BMC Public Health. 2008; 8(1): 347. DOI: 10.1186/1471-2458-8-347 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 30.Alam F, Hossain R, Ahmed H, Alam M, Sarkar M, Halbreich U. Stressors and mental health in Bangladesh: Current situation and future hopes. BJPsych International. Published online 2020: 1–4. DOI: 10.1192/bji.2020.57 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 31.Lim GY, Tam WW, Lu Y, Ho CS, Zhang MW, Ho RC. Prevalence of depression in the community from 30 countries between 1994 and 2014. Sci Rep. 2018; 8(1). DOI: 10.1038/s41598-018-21243-x [DOI] [PMC free article] [PubMed] [Google Scholar]
- 32.Sareen J, Erickson J, Medved MI, et al. Risk factors for post-injury mental health problems: Review: Post-injury mental health problems. Depress Anxiety. 2013; 30(4): 321–327. DOI: 10.1002/da.22077 [DOI] [PubMed] [Google Scholar]
- 33.Liu D, Ren Y, Yan F, et al. Psychological impact and predisposing factors of the Coronavirus disease 2019 (COVID-19) pandemic on general public in China. SSRN Electron J. Published online 2020. DOI: 10.2139/ssrn.3551415 [DOI] [Google Scholar]
- 34.Talevi D, Socci V, Carai M, et al. Mental health outcomes of the COVID-19 pandemic. Riv Psichiatr. 2020; 55(3): 137–144. [DOI] [PubMed] [Google Scholar]
- 35.Wang Y, Di Y, Ye J, Wei W. Study on the public psychological states and its related factors during the outbreak of coronavirus disease 2019 (COVID-19) in some regions of China. Psychol Health Med. Published online 2020: 1–10. DOI: 10.1080/13548506.2020.1746817 [DOI] [PubMed] [Google Scholar]
- 36.Eid RS, Gobinath AR, Galea LAM. Sex differences in depression: Insights from clinical and preclinical studies. Prog Neurobiol. 2019; 176: 86–102. DOI: 10.1016/j.pneurobio.2019.01.006 [DOI] [PubMed] [Google Scholar]
- 37.Mahase E. Covid-19: Death rate is 0. 66% and increases with age, study estimates. BMJ: British Medical Journal (Online). 2020; 369. DOI: 10.1136/bmj.m1327 [DOI] [PubMed] [Google Scholar]
- 38.Hyland P, Shevlin M, McBride O, et al. Anxiety and depression in the Republic of Ireland during the COVID-19 pandemic. Acta Psychiatr Scand. 2020; 142(3): 249–256. DOI: 10.1111/acps.13219 [DOI] [PubMed] [Google Scholar]
- 39.Ahmed MZ, Ahmed O, Aibao Z, Hanbin S, Siyu L, Ahmad A. Epidemic of COVID-19 in China and associated Psychological Problems. Asian J Psychiatr. 2020; 51(102092): 102092. DOI: 10.1016/j.ajp.2020.102092 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 40.Brooks SK, Webster RK, Smith LE, et al. The psychological impact of quarantine and how to reduce it: Rapid review of the evidence. Lancet. 2020; 395(10227): 912–920. DOI: 10.1016/S0140-6736(20)30460-8 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 41.Gao J, Zheng P, Jia Y, et al. Mental health problems and social media exposure during COVID-19 outbreak. PLoS One. 2020; 15(4): e0231924. DOI: 10.1371/journal.pone.0231924 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 42.Cava MA, Fay KE, Beanlands HJ, McCay EA, Wignall R. The experience of quarantine for individuals affected by SARS in Toronto. Public Health Nurs. 2005; 22(5): 398–406. DOI: 10.1111/j.0737-1209.2005.220504.x [DOI] [PubMed] [Google Scholar]
- 43.Islam MM, Ali M, Ferroni P, Underwood P, Alam MF. Prevalence of psychiatric disorders in an urban community in Bangladesh. Gen Hosp Psychiatry. 2003; 25(5): 353–357. DOI: 10.1016/S0163-8343(03)00067-7 [DOI] [PubMed] [Google Scholar]
- 44.Izutsu T, Tsutsumi A, Islam AM, Kato S, Wakai S, Kurita H. Mental health, quality of life, and nutritional status of adolescents in Dhaka, Bangladesh: Comparison between an urban slum and a non-slum area. Soc Sci Med. 2006; 63(6): 1477–1488. DOI: 10.1016/j.socscimed.2006.04.013 [DOI] [PubMed] [Google Scholar]
- 45.Wang C, Pan R, Wan X, et al. Immediate psychological responses and associated factors during the initial stage of the 2019 Coronavirus disease (COVID-19) epidemic among the general population in China. Int J Environ Res Public Health. 2020; 17(5): 1729. DOI: 10.3390/ijerph17051729 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 46.Zhang Y, Ma ZF. Impact of the COVID-19 pandemic on mental health and quality of life among local residents in Liaoning Province, China: A cross-sectional study. Int J Environ Res Public Health. 2020; 17(7): 2381. DOI: 10.3390/ijerph17072381 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 47.Groarke JM, Berry E, Graham-Wisener L, McKenna-Plumley PE, McGlinchey E, Armour C. Loneliness in the UK during the COVID-19 pandemic: Cross-sectional results from the COVID-19 Psychological Wellbeing Study. PLoS One. 2020; 15(9): e0239698. DOI: 10.1371/journal.pone.0239698 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 48.Fegert JM, Vitiello B, Plener PL, Clemens V. Challenges and burden of the Coronavirus 2019 (COVID-19) pandemic for child and adolescent mental health: A narrative review to highlight clinical and research needs in the acute phase and the long return to normality. Child Adolesc Psychiatry Ment Health. 2020; 14(1): 20. DOI: 10.1186/s13034-020-00329-3 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 49.Ettman CK, Abdalla SM, Cohen GH, Sampson L, Vivier PM, Galea S. Prevalence of depression symptoms in US adults before and during the COVID-19 pandemic. JAMA Netw Open. 2020; 3(9): e2019686. DOI: 10.1001/jamanetworkopen.2020.19686 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 50.Xiao H, Zhang Y, Kong D, Li S, Yang N. The effects of social support on sleep quality of medical staff treating patients with Coronavirus disease 2019 (COVID-19) in January and February 2020 in China. Med Sci Monit. 2020; 26: e923549. DOI: 10.12659/MSM.923549 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 51.Xiong J, Lipsitz O, Nasri F, et al. Impact of COVID-19 pandemic on mental health in the general population: A systematic review. J Affect Disord. 2020; 277: 55–64. DOI: 10.1016/j.jad.2020.08.001 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 52.Serafini G, Parmigiani B, Amerio A, Aguglia A, Sher L, Amore M. The psychological impact of COVID-19 on the mental health in the general population. QJM. 2020; 113(8): 531–537. DOI: 10.1093/qjmed/hcaa201 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 53.Stickley A, Koyanagi A. Loneliness, common mental disorders and suicidal behavior: Findings from a general population survey. J Affect Disord. 2016; 197: 81–87. DOI: 10.1016/j.jad.2016.02.054 [DOI] [PubMed] [Google Scholar]
- 54.Samadarshi SCA, Sharma S, Bhatta J. An online survey of factors associated with self-perceived stress during the initial stage of the COVID-19 outbreak in Nepal. The Ethiopian Journal of Health Development. 2020; 34(2). [Google Scholar]
- 55.Schäfer SK, Sopp MR, Schanz CG, Staginnus M, Göritz AS, Michael T. Impact of COVID-19 on public mental health and the buffering effect of a sense of coherence. Psychother Psychosom. 2020; 89(6): 386–392. DOI: 10.1159/000510752 [DOI] [PMC free article] [PubMed] [Google Scholar]
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Supplementary Materials
Data Availability Statement
Our data are included in the manuscript, and raw data can be released on reasonable request.