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. 2021 Feb 20;57:5–17. doi: 10.1016/j.breast.2021.02.009

Table 6.

Other recurrence outcomes in RCTs.

First Author (year) [trial name] Intergroup Difference
Intervention
Comparator
Hazard Ratio 95% CI p-value Treatment Proportion Treatment Proportion
TTR at 5 years

Ruiz-Borrego (2019) [GEICAM/2006–10] NR NR 0.406 Anastrozole 92.7% Anastrozole + fulvestrant 94.0%
BCRR at 10 years
Knoop (2014) [DBCG 77C] LA: 0.66 0.53–0.84 NR Tamoxifen + radiotherapy 40.8% Radiotherapy alone 55.1%
LB: 0.54 0.39–0.74 NR 57.0% 69.1%

Abbreviations: BCRR = breast cancer recurrence rate; CI = confidence interval; LA = luminal A; LB = luminal B/HER2-; NR = not reported; RCT = randomized controlled trial.