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. 1995 Mar 1;36(1):145–147. doi: 10.1186/BF03547711

Prostaglandin F2α Metabolite Levels Following an Embryo Transfer Procedure in the Mare

K Kask 1,✉, L Malmgren 1, K Odensvik 1
PMCID: PMC8095418  PMID: 7572452

Abstract

Hormonal, chemical, and mechanical stimuli can activate the arachidonic acid cascade and result in formation of prostaglandins and related substances. These compounds can have a profound role in the initiation of the inflammatory process (Higgins & Lees 1984). Prostaglandin (PG) F2α is the key hormone in reproductive physiology with well-known effects on reproductive performance e.g. luteolysis and abortion. An activation of the arachidonic acid cascade, caused by mechanical manipulation during an embryo transfer procedure, might be one explanation for early embryonic loss.

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Acknowledgments

Financial support for this study was provided by the Swedish Council for Forestry and Agricultural Research.

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