In our review ‘The Immunopathology of Multiple Sclerosis: an Overview’ (1) we discuss on page 213 that lymph follicle like structures in the meninges “seem to be abundant in patients with severe and rapid progression of the disease and are topographically related to areas of cortical demyelination.” This statement was based on data, which are in agreement with our own observations, but were at the time, when the review was written public only in abstract form and, therefore, not included in the reference list. The respective study, which underpins this view is now published in Brain (2).
REFERENCES
- 1. Lassmann H, Brück W, Lucchinetti C (2007) The immunopathology of multiple sclerosis: an overview. Brain Pathol 17:210–218. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2. Magliozzi R, Howell O, Vora A, Serafini B, Nicholas R, Puopoplo M, Reynolds R, Aloisi F (2007) Meningeal B‐cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain 130:1089–1104. [DOI] [PubMed] [Google Scholar]