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. 2006 Apr 5;12(2):257–259. doi: 10.1111/j.1750-3639.2002.tb00440.x

What is an Oligodendroglioma?

Peter C Burger 1
PMCID: PMC8095985  PMID: 11958379

Editor's Note:

With this issue, we begin a new series of articles entitled “Controversies in neuropathology.” These will represent brief position papers on controversial topics in our specialty. They are not intended to be review articles, rather will represent “position papers” on topical issues, with a relatively circumscribed and selective bibliography. Authors of these papers are encouraged to present and defend their own views on the subject in question. Most of these papers will be by invitation, but authors who would like to submit an article for this series are encouraged to contact the Brain Pathology editorial office. HVV

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References

  • 1. Bigner SH, Matthews MR, Rasheed BK, Wiltshire RN, Friedman HS, Friedman AH. et al (1999) Molecular genetic aspects of oligodendrogliomas including analysis by comparative genomic hybridization. Am J Pathol 155:375–386. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2. Bigner SH, Rasheed BK, Wiltshire R, McLendon RE (1999) Morphologic and molecular genetic aspects of oligodendroglial neoplasms. Neuro-oncology 1:52–60. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3. Burger P, Yates, AJ , Scheithauer, BW , Smith JS, Feuerstein, BG , Passe, SM , Jenkins, RB , Pearl, DK. Oligodendrogliomas—a correlative study of genetic and histopatholoic features. Submitted.
  • 4. Burger PC, Minn AY, Smith JS, Borell TJ, Jedlicka AE, Huntley BK et al (2001) Losses of chromosomal arms 1p and 19q in the diagnosis of oligodendroglioma. a study of paraffin‐embedded sections. Mod Pathol 14:842–853. [DOI] [PubMed] [Google Scholar]
  • 5. Cairncross JG, Ueki K, Zlatescu MC, Lisle DK, Finkelstein DM, Hammond RR et al (1998) Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J Natl Cancer Inst 90:1473–1479. [DOI] [PubMed] [Google Scholar]
  • 6. Ino Y, Betensky RA, Zlatescu MC, Sasaki H, Macdonald DR, Stemmer‐Rachamimov AO et al (2001) Molecular subtypes of anaplastic oligodendroglioma: implications for patient management at diagnosis. Clin Cancer Res 7:839–845. [PubMed] [Google Scholar]
  • 7. Jeuken JW, Sprenger SH, Boerman RH, von Deimling A, Teepen HL, van Overbeeke JJ et al (2001) Subtyping of oligo‐astrocytic tumours by comparative genomic hybridization. J Pathol 194:81–87. [DOI] [PubMed] [Google Scholar]
  • 8. Jeuken JW, Sprenger SH, Wesseling P, Macville MV, von Deimling A, Teepen HL et al (1999) Identification of subgroups of high‐grade oligodendroglial tumors by comparative genomic hybridization. J Neuropathol Exp Neurol 58:606–612. [DOI] [PubMed] [Google Scholar]
  • 9. Kraus JA, Koopmann J, Kaskel P, Maintz D, Brandner S, Schramm J. et al (1995) Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma. J Neuropathol Exp Neurol 54:91–95. [DOI] [PubMed] [Google Scholar]
  • 10. Maintz D, Fiedler K, Koopmann J, Rollbrocker B, Nechev S, Lenartz D. et al (1997) Molecular genetic evidence for subtypes of oligoastrocytomas. J Neuropathol Exp Neurol 56:1098–1104. [DOI] [PubMed] [Google Scholar]
  • 11. Reifenberger J, Reifenberger G, Liu L, James CD, Wechsler W, Collins VP (1994) Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p. Am J Pathol 145:1175–1190. [PMC free article] [PubMed] [Google Scholar]
  • 12. Ritland SR, Ganju V, Jenkins RB (1995) Region‐specific loss of heterozygosity on chromosome 19 is related to the morphologic type of human glioma. Genes Chromosomes Cancer 12:277–282. [DOI] [PubMed] [Google Scholar]
  • 13. Sasaki H, Zlatescu, MC , Betensky, RA , Johnk, LB , Cutone, AN , Cairncross, JG , Louis, DN (2002) Histopathological‐molecular genetic correlations in referral pathologist‐diagnosed low‐grade “oligodendroglioma”. J Neuropathol Exp Neurol 61:58–63. [DOI] [PubMed] [Google Scholar]
  • 14. Smith JS, Alderete B, Minn Y, Borell TJ, Perry A, Mohapatra G. et al (1999) Localization of common deletion regions on 1p and 19q in human gliomas and their association with histological subtype. Oncogene 18:4144–152. [DOI] [PubMed] [Google Scholar]
  • 15. Smith JS, Perry A, Borell TJ, Lee HK, O'Fallon J, Hosek SM et al (2000) Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas. J Clin Oncol 18:636–645. [DOI] [PubMed] [Google Scholar]
  • 16. von Deimling A, Fimmers R, Schmidt MC, Bender B, Fassbender F, Nagel J. et al (2000) Comprehensive allelotype and genetic anaysis of 466 human nervous system tumors. J Neuropathol Exp Neurol 59:544–558. [DOI] [PubMed] [Google Scholar]

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