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. Author manuscript; available in PMC: 2021 May 5.
Published in final edited form as: Science. 2020 May 1;368(6490):eaau5480. doi: 10.1126/science.aau5480

Fig. 2. Small evolutionary changes matter.

Fig. 2.

Small evolutionary changes in amino acid composition of AMPs can have major consequences for host survival during infection (30). In D. melanogaster, different alleles of Diptericin (arginine and serine) show pathogen-specific activity here against P. rettgeri. Lines of D. melanogaster with null alleles (black) show higher mortality than do lines homozygous for arginine (red). Lines homozygous for serine (blue) show the highest survival.