Visual acuities for untreated and treated eyes in the patients
(A) Light perception (LP) vision in P1 did not allow for standard ETDRS visual acuity measures, as in P2 and P3. A low-vision method, BVRT (Berkeley Rudimentary Vision Test) charts, was used instead. Scores from BVRT sessions are plotted.
(B) P2 and P3 had ETDRS (Early Treatment of Diabetic Retinopathy), and tumbling E data collected and visual acuity change from baseline are plotted. Labels on the left and right of each panel indicate the average best-corrected visual acuity at baseline and at month 9, respectively, where formal statistics were performed. Horizontal dashed lines correspond to no change; +3 and −3 ETDRS chart lines for reference. Change of one line in the ETDRS chart corresponds to 0.1 logMAR. Symbols: up-triangles, untreated eye results; down-triangles, treated eye results. The vertical line at day 0 of Treated Eye graphs represents the day of surgery. Post-operative reduction in acuity of the treated eye occurred in all patients (not plotted) but then recovered to baseline by day 7. ∗, Mean at last visit significantly different than at baseline (two sample, two-tailed t test, α = 0.05); n.s., difference not significant.