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. 2021 Apr 29;76(12):1242–1245. doi: 10.1136/thoraxjnl-2021-217031

Table 1.

Spearman correlation coefficients of radiographic and dyspnoea scores with pulmonary function, 6-minute walk distance, frailty and symptoms

DLCO (% predicted) FVC (% predicted) 6MWD (m)
CT pattern R 2 r P value R 2 r P value R 2 r P value
Ground glass opacities 0.12 −0.34 0.003* 0.06 −0.25 0.03* 0 −0.02 0.92
Reticulations 0.41 −0.64 <0.001* 0.04 −0.21 0.07 0 −0.02 0.8
Traction bronchiectasis 0.24 −0.49 <0.001* 0.05 −0.23 0.04* 0 −0.05 0.69
Frailty phenotype score Cough scale UCSD SOBQ
CT pattern R 2 r P value R 2 r P value R 2 r P value
Ground glass opacities 0.21 0.46 <0.001* 0 0.07 0.56 0.02 0.14 0.23
Reticulations 0.05 0.23 0.04* 0.07 0.26 0.02* 0 0.05 0.66
Traction bronchiectasis 0.03 0.16 0.17 0.06 0.25 0.03* 0 0.07 0.57
DLCO (% predicted) FVC (% predicted) 6MWD (m)
R 2 r P value R 2 r P value R 2 r P value
UCSD SOBQ 0.02 −0.14 0.24 0.06 −0.25 0.04* 0.06 −0.25 0.03*
Frailty phenotype score Grip strength (kg) Gait speed (m/s)
R2 r P value R2 r P value R2 r P value
UCSD SOBQ 0.22 0.47 <0.001* 0.14 −0.37 0.001* 0.05 −0.21 0.06

*Significant after controlling for false discovery using the Benjamini-Hochberg method at a false discovery rate of 0.10.

DLCO, diffusion capacity for carbon monoxide; 6MWD, 6-minute walk distance; UCSD SOBQ, University of California San Diego Shortness of Breath Questionnaire.