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International Journal of Oncology logoLink to International Journal of Oncology
. 2021 May 5;58(6):33. doi: 10.3892/ijo.2021.5213

High PLK4 expression promotes tumor progression and induces epithelial-mesenchymal transition by regulating the Wnt/β-catenin signaling pathway in colorectal cancer

Zhibin Liao, Hongwei Zhang, Pan Fan, Qibo Huang, Keshuai Dong, Yongqiang Qi, Jia Song, Lin Chen, Huifang Liang, Xiaoping Chen, Zhanguo Zhang, Bixiang Zhang
PMCID: PMC8104922  PMID: 33955524

Int J Oncol 54: 479-490, 2019; DOI: 10.3892/ijo.2018.4659

Subsequently to the publication of the above article, the author realized that Fig. 5 on p. 486 contained some errors on account of the figure having been compiled incorrectly; essentially, the published version of the figure contained incorrect images for the panels presented in Fig. 5C and E. The authors were able to re-examine their original data, and identify the data that was intended to have been shown for these figure parts.

Figure 5.

Figure 5

PLK4 promotes migration and invasion of colorectal cancer cells. (A) Effects of PLK4 knockdown on LoVo cell migration, as evaluated by wound scratch assay. (B) Effects of PLK4 overexpression on SW480 cell migration, as evaluated by wound scratch assay. (C) Effects of PLK4 knockdown on LoVo cell migration and invasion, as evaluated by Transwell assay. (D) Effects of PLK4 knockdown on SW620 cell migration and invasion, as evaluated by Transwell assay. (E) Effects of PLK4 overexpression on SW480 cell migration and invasion, as evaluated by Transwell assay. Results are presented as the means ± standard error of the mean of triplicate repeats from three independent experiments. *P<0.05, **P<0.01, ***P<0.001. CON, control; CRC, colorectal cancer; PLK4, polo-like kinase 4; sh/shRNA, short hairpin RNA; VEC, empty vector.

The corrected version of Fig. 5 is shown on the next page, featuring the correct data for Fig. 5C and E, including new bar charts showing the quantification of these data. The authors confirm that these data continue to support the main conclusions presented in their paper, and are grateful to the Editor of International Journal of Oncology for allowing them this opportunity to publish a Corrigendum. They also apologize to the readership for any inconvenience caused.


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