For each dataset, TQMD was launched with the Jaccard Index as a distance, a pack size of 200, the loose clustering mode, and was allocated a maximum of 50 CPUs. Other parameters (direct or indirect strategy and distance threshold) are provided in the table, along with the total running time in CPU hours (h.CPU), the initial number of genomes (# starting), the number of representatives obtained (# repr.), the number of ribosomal protein alignments used in the supermatrix (# prot.), and the number of unambiguously aligned amino acids in the supermatrix (# AA). Further details (taxonomy and download links, Krona taxonomic plots, Forty-Two reports, supermatrices and trees) are available at https://doi.org/10.6084/m9.figshare.13238936.