Table 2.

Echocardiographic and anatomical measurements:

HF vs sham-operated rats

	Sham	HF
Echocardiographic variables ~24 h
LVEDV (ml)	0.38 ± 0.04	0.60 ± 0.03*
LVEF	0.85 ± 0.03	0.37 ± 0.02*
%IZ	-	40 ± 2*
Echocardiographic variables at 4 weeks
LVEDV (ml)	0.39 ± 0.07	1.14 ± 0.08*§
LVEF	0.83 ± 0.03	0.36 ± 0.03*
%IZ	-	37 ± 3*
Anatomic variables at 4 weeks
BW (g)	362 ± 5	355 ± 5
LV/BW (mg/g)	2.38 ± 0.04	2.35 ± 0.13
RV/BW (mg/g)	0.53 ± 0.03	0.94 ± 0.11*
Lung/BW (mg/g)	3.41 ± 0.09	8.97 ± 1.38*

LVEDV: left ventricular end-diastolic volume; LVEF: left ventricular ejection fraction; %IZ: ischemic zone as a percent of left ventricular circumference; BW: body weight; LV: left ventricular; RV: right ventricular; Values are expressed as mean ± SEM (n = 6 for each group).

^*p<0.05, versus Sham

^§p<0.05, versus baseline at 24 hours.