Table 3.

Echocardiographic measurements:

HF + EGFR siRNA and HF + Scr siRNA rats

	HF + Scr siRNA	HF + EGFR siRNA
Variables ~24 h after MI
LVEDV (ml)	0.71 ± 0.07	0.76 ± 0.04
LVEF	0.33 ± 0.03	0.31 ± 0.02
%IZ	45 ± 3	43 ± 2
Variables 4 weeks after MI
LVEDV (ml)	1.16 ± 0.05*	1.05 ± 0.07*
LVEF	0.30 ± 0.02	0.32 ± 0.02
%IZ	46 ± 2	44 ± 1

HF + Scr siRNA, HF rats treated with scrambled siRNA; HF + EGFR siRNA, HF rats treated with EGFR siRNA. LVEDV: left ventricular end-diastolic volume; LVEF: left ventricular ejection fraction; %IZ: ischemic zone as a percent of left ventricular circumference. Values are expressed as mean ± SEM (n = 11-12 for each group).

^*p<0.05, versus baseline at 24 hours.