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. 2021 Jan 5;18(1):156–169. doi: 10.1007/s13311-020-00982-8

Table 1.

Common sleep disturbances in neurodevelopmental disorders

Neurodevelopmental disorder Sleep disturbances
Sleep-onset insomnia Sleep maintenance insomnia Sleep disordered breathing Excessive daytime sleepiness Nocturnal seizures
Angelman syndrome +++ ++ ++
Autism ++ + +
Down syndrome + +++ ++
Fragile X syndrome +++ +++ +
Prader–Willi syndrome +++ +++
Rett syndrome ++ ++ ++
Smith–Magenis syndrome +++ +++ + +++
Williams syndrome +++ ++ +