Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Juliette Coignard; Michael Lush; Jonathan Beesley; Tracy A O’Mara; Joe Dennis; Jonathan P Tyrer; Daniel R Barnes; Lesley McGuffog; Goska Leslie; Manjeet K Bolla; Muriel A Adank; Simona Agata; Thomas Ahearn; Kristiina Aittomäki; Irene L Andrulis; Hoda Anton-Culver; Volker Arndt; Norbert Arnold; Kristan J Aronson; Banu K Arun; Annelie Augustinsson; Jacopo Azzollini; Daniel Barrowdale; Caroline Baynes; Heko Becher; Marina Bermisheva; Leslie Bernstein; Katarzyna Białkowska; Carl Blomqvist; Stig E Bojesen; Bernardo Bonanni; Ake Borg; Hiltrud Brauch; Hermann Brenner; Barbara Burwinkel; Saundra S Buys; Trinidad Caldés; Maria A Caligo; Daniele Campa; Brian D Carter; Jose E Castelao; Jenny Chang-Claude; Stephen J Chanock; Wendy K Chung; Kathleen B M Claes; Christine L Clarke; GEMO Study Collaborators; EMBRACE Collaborators; J Margriet Collée; Don M Conroy; Kamila Czene; Mary B Daly; Peter Devilee; Orland Diez; Yuan Chun Ding; Susan M Domchek; Thilo Dörk; Isabel dos-Santos-Silva; Alison M Dunning; Miriam Dwek; Diana M Eccles; A Heather Eliassen; Christoph Engel; Mikael Eriksson; D Gareth Evans; Peter A Fasching; Henrik Flyger; Florentia Fostira; Eitan Friedman; Lin Fritschi; Debra Frost; Manuela Gago-Dominguez; Susan M Gapstur; Judy Garber; Vanesa Garcia-Barberan; Montserrat García-Closas; José A García-Sáenz; Mia M Gaudet; Simon A Gayther; Andrea Gehrig; Vassilios Georgoulias; Graham G Giles; Andrew K Godwin; Mark S Goldberg; David E Goldgar; Anna González-Neira; Mark H Greene; Pascal Guénel; Lothar Haeberle; Eric Hahnen; Christopher A Haiman; Niclas Håkansson; Per Hall; Ute Hamann; Patricia A Harrington; Steven N Hart; Wei He; Frans B L Hogervorst; Antoinette Hollestelle; John L Hopper

doi:10.1038/s41467-021-23162-4

. 2021 May 14;12:2986. doi: 10.1038/s41467-021-23162-4

Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Juliette Coignard ^1,^2,^3,^4,^5,⁶, Michael Lush ⁴, Jonathan Beesley ⁷, Tracy A O’Mara ⁷, Joe Dennis ⁴, Jonathan P Tyrer ⁸, Daniel R Barnes ⁴, Lesley McGuffog ⁴, Goska Leslie ⁴, Manjeet K Bolla ⁴, Muriel A Adank ⁹, Simona Agata ¹⁰, Thomas Ahearn ¹¹, Kristiina Aittomäki ¹², Irene L Andrulis ^13,¹⁴, Hoda Anton-Culver ¹⁵, Volker Arndt ¹⁶, Norbert Arnold ^17,¹⁸, Kristan J Aronson ¹⁹, Banu K Arun ²⁰, Annelie Augustinsson ²¹, Jacopo Azzollini ²², Daniel Barrowdale ⁴, Caroline Baynes ⁸, Heko Becher ²³, Marina Bermisheva ²⁴, Leslie Bernstein ²⁵, Katarzyna Białkowska ²⁶, Carl Blomqvist ^27,²⁸, Stig E Bojesen ^29,^30,³¹, Bernardo Bonanni ³², Ake Borg ³³, Hiltrud Brauch ^34,^35,³⁶, Hermann Brenner ^16,^36,³⁷, Barbara Burwinkel ^39,⁴⁰, Saundra S Buys ⁴¹, Trinidad Caldés ⁴², Maria A Caligo ⁴³, Daniele Campa ^44,⁴⁵, Brian D Carter ⁴⁶, Jose E Castelao ⁴⁷, Jenny Chang-Claude ^45,⁴⁸, Stephen J Chanock ¹¹, Wendy K Chung ⁴⁹, Kathleen B M Claes ⁵⁰, Christine L Clarke ⁵¹; GEMO Study Collaborators; EMBRACE Collaborators, J Margriet Collée ⁵², Don M Conroy ⁸, Kamila Czene ⁵³, Mary B Daly ⁵⁴, Peter Devilee ^55,⁵⁶, Orland Diez ^57,⁵⁸, Yuan Chun Ding ²⁵, Susan M Domchek ⁵⁹, Thilo Dörk ⁶⁰, Isabel dos-Santos-Silva ⁶¹, Alison M Dunning ⁸, Miriam Dwek ⁶², Diana M Eccles ⁶³, A Heather Eliassen ^64,⁶⁵, Christoph Engel ⁶⁶, Mikael Eriksson ⁵³, D Gareth Evans ^67,⁶⁸, Peter A Fasching ^69,⁷⁰, Henrik Flyger ⁷¹, Florentia Fostira ⁷², Eitan Friedman ^73,⁷⁴, Lin Fritschi ⁷⁵, Debra Frost ⁴, Manuela Gago-Dominguez ^76,⁷⁷, Susan M Gapstur ⁴⁶, Judy Garber ⁷⁸, Vanesa Garcia-Barberan ⁷⁹, Montserrat García-Closas ¹¹, José A García-Sáenz ⁷⁹, Mia M Gaudet ⁴⁶, Simon A Gayther ⁸⁰, Andrea Gehrig ⁸¹, Vassilios Georgoulias ⁸², Graham G Giles ^83,^84,⁸⁵, Andrew K Godwin ⁸⁶, Mark S Goldberg ^87,⁸⁸, David E Goldgar ⁸⁹, Anna González-Neira ⁹⁰, Mark H Greene ⁹¹, Pascal Guénel ⁹², Lothar Haeberle ⁹³, Eric Hahnen ^94,⁹⁵, Christopher A Haiman ⁹⁶, Niclas Håkansson ⁹⁸, Per Hall ^53,⁹⁸, Ute Hamann ⁹⁹, Patricia A Harrington ⁸, Steven N Hart ¹⁰⁰, Wei He ⁵³, Frans B L Hogervorst ⁹, Antoinette Hollestelle ¹⁰¹, John L Hopper ⁸⁴, Darling J Horcasitas ¹⁰², Peter J Hulick ^103,¹⁰⁴, David J Hunter ^65,^105,¹⁰⁶, Evgeny N Imyanitov ¹⁰⁷; KConFab Investigators; HEBON Investigators; ABCTB Investigators, Agnes Jager ¹⁰¹, Anna Jakubowska ^26,¹⁰⁸, Paul A James ^109,¹¹⁰, Uffe Birk Jensen ¹¹¹, Esther M John ^112,¹¹⁴, Michael E Jones ¹¹⁴, Rudolf Kaaks ⁴⁵, Pooja Middha Kapoor ^45,¹¹⁵, Beth Y Karlan ^116,¹¹⁷, Renske Keeman ¹¹⁸, Elza Khusnutdinova ^24,¹¹⁹, Johanna I Kiiski ¹²⁰, Yon-Dschun Ko ¹²¹, Veli-Matti Kosma ^122,^123,¹²⁴, Peter Kraft ^65,¹⁰⁵, Allison W Kurian ^112,¹¹⁴, Yael Laitman ⁷³, Diether Lambrechts ^125,¹²⁶, Loic Le Marchand ¹²⁷, Jenny Lester ^116,¹¹⁷, Fabienne Lesueur ^1,^2,^3,⁵, Tricia Lindstrom ¹⁰⁰, Adria Lopez-Fernández ¹²⁸, Jennifer T Loud ⁹¹, Craig Luccarini ⁸, Arto Mannermaa ^122,^123,¹²⁴, Siranoush Manoukian ²², Sara Margolin ^98,¹²⁹, John W M Martens ¹⁰¹, Noura Mebirouk ^1,^2,^3,⁵, Alfons Meindl ¹³⁰, Austin Miller ¹³¹, Roger L Milne ^83,^84,⁸⁵, Marco Montagna ¹⁰, Katherine L Nathanson ⁵⁹, Susan L Neuhausen ²⁵, Heli Nevanlinna ¹²⁰, Finn C Nielsen ¹³², Katie M O’Brien ¹³³, Olufunmilayo I Olopade ¹³⁴, Janet E Olson ¹⁰⁰, Håkan Olsson ²¹, Ana Osorio ^90,¹³⁵, Laura Ottini ¹³⁶, Tjoung-Won Park-Simon ⁶⁰, Michael T Parsons ⁷, Inge Sokilde Pedersen ^137,^138,¹³⁹, Beth Peshkin ¹⁴⁰, Paolo Peterlongo ¹⁴¹, Julian Peto ⁶¹, Paul D P Pharoah ^4,⁸, Kelly-Anne Phillips ^7,^84,¹⁰⁹, Eric C Polley ¹⁰⁰, Bruce Poppe ⁵⁰, Nadege Presneau ⁶², Miquel Angel Pujana ¹⁴², Kevin Punie ¹⁴³, Paolo Radice ¹⁴⁴, Johanna Rantala ¹⁴⁵, Muhammad U Rashid ^99,¹⁴⁶, Gad Rennert ¹⁴⁷, Hedy S Rennert ¹⁴⁷, Mark Robson ¹⁴⁸, Atocha Romero ¹⁴⁹, Maria Rossing ¹³², Emmanouil Saloustros ¹⁵⁰, Dale P Sandler ¹³³, Regina Santella ¹⁵¹, Maren T Scheuner ¹⁵², Marjanka K Schmidt ^118,¹⁵³, Gunnar Schmidt ¹⁵⁴, Christopher Scott ¹⁰⁰, Priyanka Sharma ¹⁵⁵, Penny Soucy ¹⁵⁶, Melissa C Southey ^85,¹⁵⁷, John J Spinelli ^158,¹⁵⁹, Zoe Steinsnyder ¹⁶⁰, Jennifer Stone ^84,¹⁶¹, Dominique Stoppa-Lyonnet ^162,^163,¹⁶⁴, Anthony Swerdlow ^114,¹⁶⁵, Rulla M Tamimi ^64,^65,¹⁰⁵, William J Tapper ⁶³, Jack A Taylor ^133,¹⁶⁷, Mary Beth Terry ¹⁵¹, Alex Teulé ¹⁶⁸, Darcy L Thull ¹⁶⁹, Marc Tischkowitz ^170,¹⁷¹, Amanda E Toland ¹⁷², Diana Torres ^99,¹⁷³, Alison H Trainer ^110,¹⁷⁴, Thérèse Truong ⁹², Nadine Tung ¹⁷⁵, Celine M Vachon ¹⁷⁶, Ana Vega ¹⁷⁷, Joseph Vijai ^148,¹⁶⁰, Qin Wang ⁴, Barbara Wappenschmidt ^94,⁹⁵, Clarice R Weinberg ¹⁷⁸, Jeffrey N Weitzel ¹⁷⁹, Camilla Wendt ¹²⁹, Alicja Wolk ^97,¹⁸⁰, Siddhartha Yadav ¹⁸¹, Xiaohong R Yang ¹¹, Drakoulis Yannoukakos ⁷², Wei Zheng ¹⁸², Argyrios Ziogas ¹⁵, Kristin K Zorn ¹⁸³, Sue K Park ^184,^185,¹⁸⁶, Mads Thomassen ¹⁸⁷, Kenneth Offit ^148,¹⁶⁰, Rita K Schmutzler ^94,⁹⁵, Fergus J Couch ¹⁸⁸, Jacques Simard ¹⁵, Georgia Chenevix-Trench ⁷, Douglas F Easton ^4,⁸, Nadine Andrieu ^1,^2,^3,^5,^✉, Antonis C Antoniou ^4,^✉

¹Genetic Epidemiology of Cancer team, Inserm, U900, Paris, France

²Institut Curie Paris, Paris, France

³Mines ParisTech Fontainebleau, Paris, France

⁴Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK

⁵PSL University Paris, Paris, France

⁶Paris Sud University, Orsay, France

⁷Department of Genetics and Computational Biology QIMR Berghofer Medical Research Institute, Brisbane, QLD Australia

⁸Centre for Cancer Genetic Epidemiology, Department of Oncology University of Cambridge, Cambridge, UK

⁹Family Cancer Clinic, The Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands

¹⁰Immunology and Molecular Oncology, Unit Veneto Institute of Oncology IOV – IRCCS, Padua, Italy

¹¹Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD USA

¹²Department of Clinical Genetics, Helsinki University Hospital University of Helsinki, Helsinki, Finland

¹³Fred A. Litwin Center for Cancer Genetics Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON Canada

¹⁴Department of Molecular Genetics University of Toronto, Toronto, ON Canada

¹⁵Department of Epidemiology, Genetic Epidemiology Research Institute University of California Irvine, Irvine, CA USA

¹⁶Division of Clinical Epidemiology and Aging Research German Cancer Research Center (DKFZ), Heidelberg, Germany

¹⁷Department of Gynaecology and Obstetrics University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany

¹⁸Institute of Clinical Molecular Biology University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany

¹⁹Department of Public Health Sciences, and Cancer Research Institute Queen’s University, Kingston, ON Canada

²⁰Department of Breast Medical Oncology University of Texas MD Anderson Cancer Center, Houston, TX USA

²¹Department of Cancer Epidemiology, Clinical Sciences Lund University, Lund, 22242 Sweden

²²Unit of Medical Genetics, Department of Medical Oncology and Hematology Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy

²³Institute for Medical Biometrics and Epidemiology University Medical Center Hamburg-Eppendorf, Hamburg, Germany

²⁴Institute of Biochemistry and Genetics Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia

²⁵Department of Population Sciences Beckman Research Institute of City of Hope, Duarte, CA USA

²⁶Department of Genetics and Pathology Pomeranian Medical University Szczecin, Szczecin, Poland

²⁷Department of Oncology, Helsinki University Hospital University of Helsinki, Helsinki, Finland

²⁸Department of Oncology Örebro University Hospital, Örebro, Sweden

²⁹Copenhagen General Population Study, Herlev and Gentofte Hospital Copenhagen University Hospital, Herlev, Denmark

³⁰Department of Clinical Biochemistry, Herlev and Gentofte Hospital Copenhagen University Hospital, Herlev, Denmark

³¹Faculty of Health and Medical Sciences University of Copenhagen, Copenhagen, Denmark

³²Division of Cancer Prevention and Genetics IEO, European Institute of Oncology IRCCS, Milan, Italy

³³Department of Oncology Lund University and Skåne University Hospital, Lund, Sweden

³⁴Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany

³⁵iFIT-Cluster of Excellence University of Tübingen, Tübingen, Germany

³⁶Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany

³⁷German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany

³⁹Molecular Epidemiology Group, C080 German Cancer Research Center (DKFZ), Heidelberg, Germany

⁴⁰Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg University of Heidelberg, Heidelberg, Germany

⁴¹Department of Medicine Huntsman Cancer Institute, Salt Lake City, UT USA

⁴²Molecular Oncology Laboratory CIBERONC, Hospital Clinico San Carlos, IdISSC (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Madrid, Spain

⁴³SOD Genetica Molecolare University Hospital, Pisa, Italy

⁴⁴Department of Biology University of Pisa, Pisa, Italy

⁴⁵Division of Cancer Epidemiology German Cancer Research Center (DKFZ), Heidelberg, Germany

⁴⁶Behavioral and Epidemiology Research Group American Cancer Society Atlanta, Atlanta, GA USA

⁴⁷Oncology and Genetics Unit Instituto de Investigacion Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, Vigo, Spain

⁴⁸Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH) University Medical Center Hamburg-Eppendorf, Hamburg, Germany

⁴⁹Departments of Pediatrics and Medicine, Columbia University, New York, NY USA

⁵⁰Centre for Medical Genetics Ghent University, Gent, Belgium

⁵¹Westmead Institute for Medical Research University of Sydney, Sydney, NSW Australia

⁵²Department of Clinical Genetics Erasmus University Medical Center, Rotterdam, The Netherlands

⁵³Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

⁵⁴Department of Clinical Genetics Fox Chase Cancer Center Philadelphia, Philadelphia, PA USA

⁵⁵Department of Pathology Leiden University Medical Center, Leiden, The Netherlands

⁵⁶Department of Human Genetics Leiden University Medical Center, Leiden, The Netherlands

⁵⁷Oncogenetics Group Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain

⁵⁸Clinical and Molecular Genetics Area University Hospital Vall d’Hebron, Barcelona, Spain

⁵⁹Basser Center for BRCA, Abramson Cancer Center University of Pennsylvania, Philadelphia, PA USA

⁶⁰Gynaecology Research Unit, Hannover Medical School, Hannover, Germany

⁶¹Department of Non-Communicable Disease Epidemiology London School of Hygiene and Tropical Medicine, London, UK

⁶²School of Life Sciences University of Westminster, London, UK

⁶³Faculty of Medicine University of Southampton, Southampton, UK

⁶⁴Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA USA

⁶⁵Department of Epidemiology Harvard TH Chan School of Public Health, Boston, MA USA

⁶⁶Institute for Medical Informatics, Statistics and Epidemiology University of Leipzig, Leipzig, Germany

⁶⁷Genomic Medicine, Division of Evolution and Genomic Sciences The University of Manchester, Manchester Academic Health Science Centre, Manchester Universities Foundation Trust, St Mary’s Hospital, Manchester, UK

⁶⁸Genomic Medicine, North West Genomics hub Manchester Academic Health Science Centre, Manchester Universities Foundation Trust, St Mary’s Hospital, Manchester, UK

⁶⁹David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology University of California at Los Angeles, Los Angeles, CA USA

⁷⁰Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN University Hospital Erlangen, Friedrich-Alexander-University, Erlangen-Nuremberg, Erlangen, Germany

⁷¹Department of Breast Surgery, Herlev and Gentofte Hospital Copenhagen University Hospital, Herlev, Denmark

⁷²Molecular Diagnostics Laboratory, INRASTES National Centre for Scientific Research íDemokritosí, Athens, Greece

⁷³The Susanne Levy Gertner Oncogenetics Unit Chaim Sheba Medical Center, Ramat Gan, Israel

⁷⁴Sackler Faculty of Medicine Tel Aviv University, Ramat Aviv, Israel

⁷⁵School of Public Health Curtin University, Perth, Western Australia Australia

⁷⁶Genomic Medicine Group, Galician Foundation of Genomic Medicine Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain

⁷⁷Moores Cancer Center University of California, San Diego La Jolla, CA USA

⁷⁸Division of Cancer Genetics and Prevention, Dana-Farber Cancer Institute, Boston, MA USA

⁷⁹Medical Oncology Department, Hospital Clínico San Carlos Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

⁸⁰Center for Bioinformatics and Functional Genomics and the Cedars Sinai Genomics Core Cedars-Sinai Medical Center, Los Angeles, CA USA

⁸¹Department of Human Genetics University Würzburg, Würzburg, Germany

⁸²Department of Medical Oncology University Hospital of Heraklion, Heraklion, Greece

⁸³Cancer Epidemiology Division Cancer Council Victoria, Melbourne, VIC Australia

⁸⁴Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC Australia

⁸⁵Precision Medicine, School of Clinical Sciences at Monash Health Monash University, Clayton, VIC Australia

⁸⁶Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS USA

⁸⁷Department of Medicine, McGill University, Montréal, QC Canada

⁸⁸Division of Clinical Epidemiology, Royal Victoria Hospital McGill University Montréal, Montréal, QC Canada

⁸⁹Huntsman Cancer Institute and Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT USA

⁹⁰Human Cancer Genetics Programme Spanish National Cancer Research Centre (CNIO), Madrid, Spain

⁹¹Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics National Cancer Institute, Bethesda, MD USA

⁹²Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP) INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France

⁹³Department of Gynaecology and Obstetrics, University Hospital Erlangen Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany

⁹⁴Center for Hereditary Breast and Ovarian Cancer Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

⁹⁵Center for Integrated Oncology (CIO) Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

⁹⁶Department of Preventive Medicine, Keck School of Medicine University of Southern California, Los Angeles, CA USA

⁹⁷Institute of Environmental Medicine Karolinska Institutet, Stockholm, Sweden

⁹⁸Department of Oncology, Södersjukhuset, Stockholm, Sweden

⁹⁹Molecular Genetics of Breast Cancer German Cancer Research Center (DKFZ), Heidelberg, Germany

¹⁰⁰Department of Health Sciences Research, Mayo Clinic, Rochester, MN USA

¹⁰¹Department of Medical Oncology, Family Cancer Clinic Erasmus MC Cancer Institute, Rotterdam, The Netherlands

¹⁰²New Mexico Oncology Hematology Consultants, University of New Mexico, Albuquerque, NM USA

¹⁰³Center for Medical Genetics NorthShore University HealthSystem, Evanston, IL USA

¹⁰⁴The University of Chicago Pritzker School of Medicine Chicago, Chicago, IL USA

¹⁰⁵Program in Genetic Epidemiology and Statistical Genetics Harvard TH Chan School of Public Health Boston, Boston, MA USA

¹⁰⁶Nuffield Department of Population Health University of Oxford, Oxford, UK

¹⁰⁷NN Petrov Institute of Oncology, St. Petersburg, Russia

¹⁰⁸Independent Laboratory of Molecular Biology and Genetic Diagnostics Pomeranian Medical University, Szczecin, Poland

¹⁰⁹Sir Peter MacCallum Department of Oncology The University of Melbourne, Melbourne, VIC Australia

¹¹⁰Parkville Familial Cancer Centre Peter MacCallum Cancer Center, Melbourne, VIC Australia

¹¹¹Department of Clinical Genetics Aarhus, University Hospital, Aarhus, Denmark

¹¹²Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA USA

¹¹⁴Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA USA

¹¹⁵Division of Genetics and Epidemiology The Institute of Cancer Research, London, UK

¹¹⁶Faculty of Medicine University of Heidelberg, Heidelberg, Germany

¹¹⁷David Geffen School of Medicine, Department of Obstetrics and Gynecology University of California at Los Angeles, Los Angeles, CA USA

¹¹⁸Womenís Cancer Program at the Samuel Oschin Comprehensive Cancer Institute Cedars-Sinai Medical Center, Los Angeles, CA USA

¹¹⁹Division of Molecular Pathology The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands

¹²⁰Department of Genetics and Fundamental Medicine Bashkir State Medical University, Ufa, Russia

¹²¹Department of Obstetrics and Gynecology, Helsinki University Hospital University of Helsinki, Helsinki, Finland

¹²²Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH Johanniter Krankenhaus, Bonn, Germany

¹²³Translational Cancer Research Area University of Eastern Finland, Kuopio, Finland

¹²⁴Institute of Clinical Medicine, Pathology and Forensic Medicine University of Eastern Finland, Kuopio, Finland

¹²⁵VIB Center for Cancer Biology, Leuven, Belgium

¹²⁶Laboratory for Translational Genetics, Department of Human Genetics University of Leuven, Leuven, Belgium

¹²⁷Epidemiology Program University of Hawaii Cancer Center, Honolulu, HI USA

¹²⁸High Risk and Cancer Prevention Group Vall d’Hebron Institute of Oncology, Barcelona, Spain

¹²⁹Department of Clinical Science and Education, Södersjukhuset Karolinska Institutet, Stockholm, Sweden

¹³⁰Department of Gynecology and Obstetrics University of Munich, Campus Grosshadern, Munich, Germany

¹³¹NRG Oncology, Statistics and Data Management Center Roswell Park Cancer Institute, Buffalo, NY USA

¹³²Center for Genomic Medicine Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark

¹³³Epidemiology Branch National Institute of Environmental Health Sciences, NIH Research Triangle Park, Durham, NC USA

¹³⁴Center for Clinical Cancer Genetics The University of Chicago, Chicago, IL USA

¹³⁵Centro de Investigación en Red de Enfermedades Raras (CIBERER), Madrid, Spain

¹³⁶Department of Molecular Medicine University La Sapienza, Rome, Italy

¹³⁷Molecular Diagnostics Aalborg University Hospital, Aalborg, Denmark

¹³⁸Clinical Cancer Research Center Aalborg University Hospital, Aalborg, Denmark

¹³⁹Department of Clinical Medicine Aalborg University, Aalborg, Denmark

¹⁴⁰Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC USA

¹⁴¹Genome Diagnostics Program IFOM - the FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy

¹⁴²Translational Research Laboratory IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, CIBERONC, Barcelona, Spain

¹⁴³Leuven Multidisciplinary Breast Center, Department of Oncology Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium

¹⁴⁴Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy

¹⁴⁵Clinical Genetics Karolinska Institutet, Stockholm, Sweden

¹⁴⁶Department of Basic Sciences Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, Pakistan

¹⁴⁷Clalit National Cancer Control Center Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel

¹⁴⁸Clinical Genetics Service, Department of Medicine Memorial Sloan-Kettering Cancer Center, New York, NY USA

¹⁴⁹Medical Oncology Department Hospital Universitario Puerta de Hierro, Madrid, Spain

¹⁵⁰Department of Oncology University Hospital of Larissa, Larissa, Greece

¹⁵¹Department of Epidemiology, Mailman School of Public Health Columbia University, New York, NY USA

¹⁵²Cancer Genetics and Prevention Program University of California San Francisco, San Francisco, CA USA

¹⁵³Division of Psychosocial Research and Epidemiology The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands

¹⁵⁴Institute of Human Genetics Hannover Medical School, Hannover, Germany

¹⁵⁵Department of Internal Medicine, Division of Medical Oncology University of Kansas Medical Center, Westwood, KS USA

¹⁵⁶Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval Research Center, Québec City, QC Canada

¹⁵⁷Department of Clinical Pathology The University of Melbourne, Melbourne, VIC Australia

¹⁵⁸Population Oncology BC Cancer, Vancouver, BC Canada

¹⁵⁹School of Population and Public Health University of British Columbia, Vancouver, BC Canada

¹⁶⁰Clinical Genetics Research Lab, Department of Cancer Biology and Genetics Memorial Sloan-Kettering Cancer Center, New York, NY USA

¹⁶¹The Curtin UWA Centre for Genetic Origins of Health and Disease Curtin University and University of Western Australia, Perth, Western Australia Australia

¹⁶²Service de Génétique Institut Curie, Paris, France

¹⁶³Department of Tumour Biology INSERM U830, Paris, France

¹⁶⁴Université Paris Descartes, Paris, France

¹⁶⁵Division of Breast Cancer Research Institute of Cancer Research, London, UK

¹⁶⁷Epigenetic and Stem Cell Biology Laboratory National Institute of Environmental Health Sciences, NIH Research Triangle Park, Triangle Park, NC USA

¹⁶⁸Hereditary Cancer Program ONCOBELL-IDIBELL-IDIBGI-IGTP, Catalan Institute of Oncology, CIBERONC, Barcelona, Spain

¹⁶⁹Department of Medicine Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA USA

¹⁷⁰Program in Cancer Genetics, Departments of Human Genetics and Oncology McGill University, Montréal, QC Canada

¹⁷¹Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Center, University of Cambridge, Cambridge, UK

¹⁷²Department of Cancer Biology and Genetics The Ohio State University, Columbus, OH USA

¹⁷³Institute of Human Genetics Pontificia Universidad Javeriana, Bogota, Colombia

¹⁷⁴Department of medicine University Of Melbourne, Melbourne, VIC Australia

¹⁷⁵Department of Medical Oncology Beth Israel Deaconess Medical Center, Boston, MA USA

¹⁷⁶Department of Health Science Research, Division of Epidemiology Mayo Clinic, Rochester, MN USA

¹⁷⁷Fundación Pública Galega Medicina Xenómica-SERGAS, Instituto de Investigación Sanitaria Santiago de Compostela (IDIS); CIBERER, Santiago de Compostela, Spain

¹⁷⁸Biostatistics and Computational Biology Branch National Institute of Environmental Health Sciences, NIH Research Triangle Park, Triangle Park, NC USA

¹⁷⁹Clinical Cancer Genomics City of Hope, Duarte, CA USA

¹⁸⁰Department of Surgical Sciences Uppsala University, Uppsala, Sweden

¹⁸¹Department of Oncology Mayo Clinic, Rochester, MN USA

¹⁸²Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center Vanderbilt University School of Medicine, Nashville, TN USA

¹⁸³Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA USA

¹⁸⁴Department of Preventive Medicine Seoul National University College of Medicine, Seoul, Korea

¹⁸⁵Department of Biomedical Sciences Seoul National University Graduate School, Seoul, Korea

¹⁸⁶Cancer Research Institute Seoul National University, Seoul, Korea

¹⁸⁷Department of Clinical Genetics Odense University Hospital, Odence C, Denmark

¹⁸⁸Department of Laboratory Medicine and Pathology Mayo Clinic, Rochester, MN USA

¹⁸⁹Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon - Centre Léon Bérard, Lyon, France

¹⁹⁰Institut Gustave Roussy, Villejuif, France

¹⁹¹Centre Jean Perrin, Clermont–Ferrand, France

¹⁹²Centre Léon Bérard, Lyon, France

¹⁹³Centre François Baclesse, Caen, France

¹⁹⁴Institut Paoli Calmettes, Marseille, France

¹⁹⁵CHU Arnaud-de-Villeneuve, Montpellier, France

¹⁹⁶Centre Oscar Lambret, Lille, France

¹⁹⁷Centre Paul Strauss, Strasbourg, France

¹⁹⁸Institut Bergonié, Bordeaux, France

¹⁹⁹Institut Claudius Regaud, Toulouse, France

²⁰⁰CHU, Grenoble, France

²⁰¹CHU, Dijon, France

²⁰²CHU, St-Etienne, France

²⁰³Hôtel Dieu Centre Hospitalier, Chambéry, France

²⁰⁴Centre Antoine Lacassagne, Nice, France

²⁰⁵CHU, Limoges, France

²⁰⁶CHU, Nantes, France

²⁰⁷CHU Bretonneau, Tours, France

²⁰⁸Centre Hospitalier de, Bourges, France

²⁰⁹Groupe Hospitalier Pitié- Salpétrière, Paris, France

²¹⁰CHU Vandoeuvre-, les-Nancy, France

²¹¹CHU, Besançon, France

²¹²CHU Poitiers, Centre Hospitalier d’Angoulême, Poitiers, France

²¹³Centre Hospitalier de Niort, Niort, France

²¹⁴Centre Hospitalier de La Rochelle, La Rochelle, France

²¹⁵CHU Nîmes Carémeau, Nîmes, France

²¹⁶CHU, Poissy, France

²¹⁷CHU, Angers, France

²¹⁸North of Scotland Regional Genetics Service, NHS Grampian & University of Aberdeen, Foresterhill, Aberdeen, UK

²¹⁹Northern Ireland Regional Genetics Centre, Belfast Health and Social Care Trust, and Department of Medical Genetics, Queens University Belfast, Belfast, UK

²²⁰West Midlands Regional Genetics Service, Birmingham Women’s Hospital Healthcare NHS Trust, Edgbaston, Birmingham, UK

²²¹Clinical Genetics Department, St Michael’s Hospital, Bristol, UK

²²²All Wales Medical Genetics Services, University Hospital of Wales, Cardiff, UK

²²³Academic Unit of Clinical and Molecular Oncology, Trinity College Dublin and St James’s Hospital, Dublin, Eire

²²⁴South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, UK

²²⁵Department of Clinical Genetics, Royal Devon & Exeter Hospital, Exeter, UK

²²⁶Clinical Genetics, Southern General Hospital, Glasgow, UK

²²⁷Clinical Genetics, Guy’s and St. Thomas’ NHS Foundation Trust, London, UK

²²⁸North West Thames Regional Genetics Service, Kennedy-Galton Centre, Harrow, UK

²²⁹Leicestershire Clinical Genetics Service, University Hospitals of Leicester NHS Trust, Leicester, UK

²³⁰Yorkshire Regional Genetics Service, Leeds, UK

²³¹Department of Clinical Genetics, Alder Hey Hospital, Eaton Road, Liverpool, UK

²³²Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK

²³³North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London, UK

²³⁴Nottingham Clinical Genetics Service, Nottingham University Hospitals NHS Trust, Nottingham, UK

²³⁵Institute of Genetic Medicine, Centre for Life, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK

²³⁶Oxford Regional Genetics Service, Churchill Hospital, Oxford, UK

²³⁷Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK

²³⁸Sheffield Clinical Genetics Service, Sheffield Children’s Hospital, Sheffield, UK

²³⁹South West Thames Regional Genetics Service, St.Georges Hospital, Cranmer Terrace, Tooting, London, UK

²⁴⁰All Wales Medical Genetics Services, Singleton Hospital, Swansea, UK

²⁴¹All Wales Medical Genetics Service, Glan Clwyd Hospital, Rhyl, UK

²⁴²Peter MacCallum Cancer Centre, Melbourne, Australia

²⁴³Westmead Millenium Institute, Sydney, Australia

²⁴⁴BCNA delegate, Community Representative, Melbourne, Australia

²⁴⁵Westmead Hospital, Sydney, Australia

²⁴⁶Walter and Eliza Hall Institute, Melbourne, Australia

²⁴⁷University of Sydney, Sydney, Australia

²⁴⁸Melbourne Health, Melbourne, Australia

²⁴⁹Garvan Institute of Medical Research, Sydney, Australia

²⁵⁰Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands

²⁵¹Department of Clinical Genetics, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, The Netherlands

²⁵²Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands

²⁵³Department of Pathology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, The Netherlands

²⁵⁴Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands

²⁵⁵Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands

²⁵⁶Department of Clinical Genetics, MUMC, Maastricht, The Netherlands

²⁵⁷Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, The Netherlands

²⁵⁸Department of Oncological Epidemiology, University Medical Center, Groningen University, Groningen, The Netherlands

²⁵⁹Department of Clinical Genetics, VU University Medical Centre, Amsterdam, The Netherlands

²⁶⁰Department of Radiology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, The Netherlands

²⁶¹Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands

²⁶²Department of Gynaecological Oncology, University Medical Center, Groningen University, Groningen, The Netherlands

²⁶³Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, The Netherlands

²⁶⁴Department of Oncological and Endocrine Surgery, University Medical Center Utrecht, Utrecht, The Netherlands

²⁶⁵Department of Radiotherapy, Netherlands Cancer Institute, Amsterdam, The Netherlands

²⁶⁶The Netherlands Comprehensive Cancer Organization (IKNL), Utrecht, The Netherlands

²⁶⁷Foundation PALGA (The Nationwide Network and Registry of Histo- and Cytopathology in the Netherlands), Houten, The Netherlands

²⁶⁸University of Technology Sydney, Translational Oncology Group, School of Life Sciences, Faculty of Science, Ultimo, NSW Australia

²⁶⁹School of Biomedical Sciences, University of Newcastle, Newcastle; Hunter Medical Research Institute and NSW Health Pathology North, Newcastle, Australia

²⁷⁰Kolling Institute of Medical Research, University of Sydney, St Leonards, NSW Australia

²⁷¹Department of Medical Oncology, The Canberra Hospital, Canberra, ACT Australia

²⁷²Scientific Platforms, The Westmead Institute for Medical Research, The University of Sydney, Sydney, NSW Australia

²⁷³The Canberra Hospital, Garran, ACT; The Australian National University, Canberra, ACT Australia

²⁷⁴Westmead Breast Cancer Institute, Western Sydney Local Health District, Westmead, New South Wales, Australia

²⁷⁵University of Sydney, Western Clinical School, Westmead, New South Wales, Australia

²⁷⁶UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD Australia

^✉

Corresponding author.

PMCID: PMC8121813 PMID: 33990587

Abstract

A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-23162-4

Subject terms: Breast cancer, Cancer epidemiology, Cancer genetics, Risk factors

Correction to: Nature Communications 10.1038/s41467-020-20496-3, published online 17 February 2021.

The original version of this Article contained an error in the spelling of the author Heiko Becher, which was incorrectly given as Heko Becher. This has now been corrected in both the PDF and HTML versions of the Article.

Contributor Information

Nadine Andrieu, Email: nadine.andrieu@curie.fr.

Antonis C. Antoniou, Email: aca20@medschl.cam.ac.uk

GEMO Study Collaborators:

Ophélie Bertrand, Sandrine Caputo, Anaïs Dupré, Marine Le Mentec, Muriel Belotti, Anne-Marie Birot, Bruno Buecher, Emmanuelle Fourme, Marion Gauthier-Villars, Lisa Golmard, Claude Houdayer, Virginie Moncoutier, Antoine de Pauw, Claire Saule, Olga Sinilnikova, Sylvie Mazoyer, Francesca Damiola, Laure Barjhoux, Carole Verny-Pierre, Mélanie Léone, Nadia Boutry-Kryza, Alain Calender, Sophie Giraud, Olivier Caron, Marine Guillaud-Bataille, Brigitte Bressac-de-Paillerets, Yves- Jean Bignon, Nancy Uhrhammer, Christine Lasset, Valérie Bonadona, Pascaline Berthet, Dominique Vaur, Laurent Castera, Tetsuro Noguchi, Cornel Popovici, Hagay Sobol, Violaine Bourdon, Tetsuro Noguchi, Audrey Remenieras, Catherine Noguès, Isabelle Coupier, Pascal Pujol, Aurélie Dumont, Françoise Révillion, Claude Adenis, Danièle Muller, Emmanuelle Barouk-Simonet, Françoise Bonnet, Virginie Bubien, Nicolas Sevenet, Michel Longy, Christine Toulas, Rosine Guimbaud, Laurence Gladieff, Viviane Feillel, Dominique Leroux, Hélène Dreyfus, Christine Rebischung, Magalie Peysselon, Fanny Coron, Laurence Faivre, Amandine Baurand, Caroline Jacquot, Geoffrey Bertolone, Sarab Lizard, Fabienne Prieur, Marine Lebrun, Caroline Kientz, Sandra Fert Ferrer, Véronique Mari, Laurence Vénat-Bouvet, Capucine Delnatte, Stéphane Bézieau, Isabelle Mortemousque, Florence Coulet, Chrystelle Colas, Florent Soubrier, Mathilde Warcoin, Johanna Sokolowska, Myriam Bronner, Marie-Agnès Collonge-Rame, Alexandre Damette, Paul Gesta, Hakima Lallaoui, Jean Chiesa, Denise Molina-Gomes, and Olivier Ingster

EMBRACE Collaborators:

Helen Gregory, Zosia Miedzybrodzka, Patrick J. Morrison, Kai-ren Ong, Alan Donaldson, Mark T. Rogers, M. John Kennedy, Mary E. Porteous, Carole Brewer, Rosemarie Davidson, Louise Izatt, Angela Brady, Julian Barwell, Julian Adlard, Claire Foo, Fiona Lalloo, Lucy E. Side, Jacqueline Eason, Alex Henderson, Lisa Walker, Rosalind A. Eeles, Jackie Cook, Katie Snape, Diana Eccles, Alex Murray, and Emma McCann

KConFab Investigators:

Stephen Fox, Ian Campbell, Amanda Spurdle, Penny Webb, Anna de Fazio, Margaret Tassell, Judy Kirk, Geoff Lindeman, Melanie Price, Melissa Southey, Roger Milne, Sid Deb, and David Bowtell

HEBON Investigators:

Annemieke H. van der Hout, Ans M. W. van den Ouweland, Arjen R. Mensenkamp, Carolien H. M. van Deurzen, Carolien M. Kets, Caroline Seynaeve, Christi J. van Asperen, Cora M. Aalfs, Encarna B. Gómez Garcia, Flora E. van Leeuwen, G. H. de Bock, Hanne E. J. Meijers-Heijboer, Inge M. Obdeijn, J. Margriet Collée, J. J. P. Gille, Jan C. Oosterwijk, Juul T. Wijnen, Lizet E. van der Kolk, Maartje J. Hooning, Margreet G. E. M. Ausems, Marian J. E. Mourits, Marinus J. Blok, Matti A. Rookus, Muriel A. Adank, Rob B. van der Luijt, T. C. T. E. F. van Cronenburg, Carmen C. van der Pol, Nicola S. Russell, Sabine Siesling, Lucy Overbeek, R. Wijnands, and Judith L. de Lange

ABCTB Investigators:

Christine Clarke, Dinny Graham, Mythily Sachchithananthan, Deborah Marsh, Rodney Scott, Robert Baxter, Desmond Yip, Jane Carpenter, Alison Davis, Nirmala Pathmanathan, and Peter Simpson

PERMALINK

Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Juliette Coignard

Michael Lush

Jonathan Beesley

Tracy A O’Mara

Joe Dennis

Jonathan P Tyrer

Daniel R Barnes

Lesley McGuffog

Goska Leslie

Manjeet K Bolla

Muriel A Adank

Simona Agata

Thomas Ahearn

Kristiina Aittomäki

Irene L Andrulis

Hoda Anton-Culver

Volker Arndt

Norbert Arnold

Kristan J Aronson

Banu K Arun

Annelie Augustinsson

Jacopo Azzollini

Daniel Barrowdale

Caroline Baynes

Heko Becher

Marina Bermisheva

Leslie Bernstein

Katarzyna Białkowska

Carl Blomqvist

Stig E Bojesen

Bernardo Bonanni

Ake Borg

Hiltrud Brauch

Hermann Brenner

Barbara Burwinkel

Saundra S Buys

Trinidad Caldés

Maria A Caligo

Daniele Campa

Brian D Carter

Jose E Castelao

Jenny Chang-Claude

Stephen J Chanock

Wendy K Chung

Kathleen B M Claes

Christine L Clarke

J Margriet Collée

Don M Conroy

Kamila Czene

Mary B Daly

Peter Devilee

Orland Diez

Yuan Chun Ding

Susan M Domchek

Thilo Dörk

Isabel dos-Santos-Silva

Alison M Dunning

Miriam Dwek

Diana M Eccles

A Heather Eliassen

Christoph Engel

Mikael Eriksson

D Gareth Evans

Peter A Fasching

Henrik Flyger

Florentia Fostira

Eitan Friedman

Lin Fritschi

Debra Frost

Manuela Gago-Dominguez

Susan M Gapstur

Judy Garber

Vanesa Garcia-Barberan

Montserrat García-Closas

José A García-Sáenz

Mia M Gaudet

Simon A Gayther

Andrea Gehrig