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Naproxen binds to recombinant N-terminal domain of SARS-CoV-2 N. (A): Close-up view of naproxen interacting with W52 (PDB 6VYO). (B): Normalized intrinsic fluorescence of N, corrected for the inner filter effect, as a function of naproxen concentration using 2.1 µM N in 20 mM Tris buffer pH = 7.9, 100 mM NaCl. (C): evaluation of the solvent-accessible surface area in the N dimer without and with naproxen.
