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. 1991 Mar 1;32(1):27–34. doi: 10.1186/BF03546994

Pestivirus Infections in Norway. Serological Investigations in Cattle, Sheep and Pigs

Infeksjonar med pestivirus i Noreg. Serologiske undersøkingar hos storfe, sau og gris

T Løken 1,✉, J Krogsrud 1, I L Larsen 1
PMCID: PMC8127921  PMID: 1659160

Abstract

Serum samples from 1133 dairy cows (187 herds), 3712 ewes (103 flocks) and 1317 adult pigs (877 herds), were tested for neutralizing antibodies against the NADL strain of bovine virus diarrhoea virus. The prevalence rate of seropositive animals was 18.5% in cattle, 4.5% in sheep and 2.2% in pigs, such seroreactors being found in 28 % of the cattle herds and 18 % of the sheep flocks. In all three species the rate showed considerable herd and geographical variation. In cattle the seroreactor rate was similar in herds with normal reproduction and in 62 herds with problems of repeat breeding.

Of 31 pig sera containing antibodies against the NADL strain, 27 were also positive in a neutralization test for antibodies against swine fever virus (Baker strain). However, all sera showed a higher titre of antibodies against the bovine strain than against the swine fever virus. It was concluded that the immune response of the pigs had been induced by ruminant pestivirus, and not by swine fever virus.

Keywords: bovine virus diarrhoea, border disease, swine fever, neutralizing antibodies

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