On Page 3661, Materials and methods section, under the heading of the “Enzyme-Linked ImmunoSorbent Assay (ELISA)”, the sentences of Line 4-5 should be “Human Apelin ELISA Kits (SBJ-H0192; Senbeijia Biological, Nanjing, China)”.
The correct Figure 6 have provided. On Page 3669, the last picture of Figure 6B and 6D should be “LV003-Apelin DMSO hsa-miR-424 mimics”.
Figure 6.
miR-424 modulates KGN cell proliferation and apoptosis by suppressing Apelin expression. A. Changes in KGN cell proliferation rate after being treated with multiple combinations of miR-424 inhibitors, LV003-Apelin overexpression construct, and Apelin 13 peptides. Cell proliferation was analyzed by MTS. B, C. Alterations in KGN cell cycle progression after being treated with multiple combinations of miR-424 inhibitors, LV003-Apelin construct, and Apelin 13 peptides. Cell cycle progression was assessed by flow cytometry. D, E. Regulation of KGN cell apoptosis by multiple combinations of miR-424 inhibitors, LV003-Apelin construct, and Apelin 13 peptides. Cell apoptosis was evaluated by flow cytometry. NC: negative control; ns: non-significant difference; * and # indicate P < 0.05.