Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 18;24(6):102550. doi: 10.1016/j.isci.2021.102550

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Colocalization analysis

Manhattan plots of two severe COVID-19 GWAS loci (A) chr11-771716-A-C (B) chr1-161253626-C-T and their respective colocalized immune eQTLs from the eQTL Catalogue (colocalization probability >0.8). Each point represents an SNP across a genomic range, and color indicates the degree of LD (r²) with the proxy GWAS SNPs in each locus (indicated by crossed diamonds). In the eQTL rows, crossed diamonds indicate the lead QTL SNP (with the smallest association p value for a given gene).