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. 2021 Apr 28:ciab309. doi: 10.1093/cid/ciab309

Performance of Repeat BinaxNOW SARS-CoV-2 Antigen Testing in a Community Setting, Wisconsin, November-December 2020

Melisa M Shah 1,2,✉, Phillip P Salvatore 1,2, Laura Ford 1,2, Emiko Kamitani 1, Melissa J Whaley 1, Mitchell Kaitlin 1,3, Dustin W Currie 1,2, Clint N Morgan 1, Hannah E Segaloff 1,2,4, Shirley Lecher 1, Tarah Somers 1, Miriam E Van Dyke 1,2, John Paul Bigouette 1,2, Augustina Delaney 1, Juliana DaSilva 1, Michelle O’Hegarty 1, Lauren Boyle-Estheimer 1, Fatima Abdirizak 1, Sandor E Karpathy 1, Jennifer Meece 5, Lynn Ivanic 5, Kimberly Goffard 6, Doug Gieryn 6, Alana Sterkel 7, Allen Bateman 7, Juliana Kahrs 8, Kimberly Langolf 8, Tara Zochert 8, Nancy W Knight 1, Christopher H Hsu 1, Hannah L Kirking 1, Jacqueline E Tate 1
PMCID: PMC8135465  PMID: 33909068

Abstract

Repeating the BinaxNOW antigen test for SARS-CoV-2 by two groups of readers within 30 minutes resulted in high concordance (98.9%) in 2,110 encounters. BinaxNOW test sensitivity was 77.2% (258/334) compared to real-time reverse transcription-polymerase chain reaction. Same day antigen testing did not significantly improve test sensitivity while specificity remained high.

Keywords: SARS-CoV-2, antigen testing, COVID-19, BinaxNOW, diagnostic performance

Articles from Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America are provided here courtesy of Oxford University Press

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