Eur Heart J 2021; doi:10.1093/eurheartj/ehab030
In the originally published version of this manuscript, there were several errors that are listed in this corrigendum.
In the Abstract, the following sentence was incorrect: “A genetic risk score constructed from the number of risk alleles at these four DCM loci revealed a 27% increased risk of DCM for individuals with 8 risk alleles compared to individuals with 5 risk alleles (median of the referral population).” It should read: “A genetic risk score constructed from the number of risk alleles at these four DCM loci revealed a 3-fold increased risk of DCM for individuals with 8 risk alleles compared to individuals with 5 risk alleles (median of the referral population).”
In the Results section, ‘Genetic risk score analysis’ paragraph, the following sentence was incorrect: “Briefly, the unweighted GRS showed a 27% increased risk of DCM for subjects with 8 risk alleles (1.27 [1.14–1.42]) and a 21% decreased for those having only one risk allele (0.79 [0.66–0.95]) as compared with individuals with 5 risk alleles (median of the referral population) (Figure 2A, Table S7A).” It should read: “Briefly, the unweighted GRS showed a 3-fold increased risk of DCM for subjects with 8 risk alleles (3.34 [1.87–6.00]) and a 5-fold decreased for those having only one risk allele (0.21 [0.06–0.77]) as compared with individuals with 5 risk alleles (median of the referral population) (Figure 2A, Table S7A).”
In the Supplementary data, Results section, ‘GRS association analysis in the replication studies’ paragraph, the following sentence was incorrect: “Nevertheless, an unweighted GRS of 7 was associated with an increased risk of DCM of OR = 1.13 [1.09–1.18], OR = 1.19 [1.08–1.32] and OR = 1.57 [0.9–2.73] and conversely an unweighted GRS of 2 with a decreased risk of DCM, OR = 0.85 [0.79–0.92], OR = 0.96 [0.81–1.13] and OR = 0.42 [0.17–1.07], in the discovery, iGeneTRAiN and SFB_TR19 German cohorts, respectively (Table S7A). Results were similar for the weighted GRS analysis (Table S7B)”. It should read: “Nevertheless, an unweighted GRS of 7 was associated with an increased risk of DCM of OR = 1.78 [1.46–2.18], OR = 3.70 [1.59–8.67] and OR = 1.57 [0.9–2.73] and conversely an unweighted GRS of 2 with a decreased risk of DCM, OR = 0.38 [0.23–0.61], OR = 0.51 [0.12–2.21] and OR = 0.42 [0.17–1.07], in the discovery, iGeneTRAiN and SFB_TR19 German cohorts, respectively (Table S7A). Results were similar for the weighted GRS analysis (Table S7B).”
These errors were also present in Figure 2, and in Table S7 and Figure S13 in the Supplementary data, and have been replaced with corrected versions online.