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Acta Veterinaria Scandinavica logoLink to Acta Veterinaria Scandinavica
. 1989 Mar 1;30(1):109–110. doi: 10.1186/BF03548075

Serological Investigation of Corynebacterium Pseudotuberculosis Infection in Sheep–Correlation between the Hemolysis Inhibition Test and the ELISA Test

J K N Kuria 114,214,, G Holstad 114,214
PMCID: PMC8142189  PMID: 2675582

Abstract

Corynebacterium pseudotuberculosis causes caseous lymphadenitis in sheep and goats. The animals may be infected without showing clinical symptoms. Several serotests have therefore been employed to detect infected animals. Shen et al (1982) performed an enzyme linked immunosorbent assay (ELISA) to detect antibodies against the organism using cell wall antigens. Maki et al (1985) found that the toxin of the bacterium was a better antigen for assessing infection in the ELISA test. They reported that the antitoxin ELISA appeared to be as sensitive as the antihemolysin inhibition test (Zaki 1968).

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Acknowledgement

We thank Johan Krogsrud and Trude Bakke for providing sera for the investigation.

References

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