Abstract
The effect of detomidine on the electrical activity of the uterus was studied during the last trimester of pregnancy in 6 mares.
The effect was observed in 3–5 min after the i.m. injection and it lasted for 50–70 min. 20 and 40 μg/kg b.w. doses of detomidine decreased the myometrial electrical activity, whereas 60 μg/kg dose did not have any effect on the activity.
The results suggested that 20, 40 and 60 μg/kg b.w. doses of detomidine can be administered to mares during the last trimester of pregnancy without the risk of abortion induced by increased uterine electrical activity.
Keywords: α-agonist, equine sedation, myometrial contractions.
Sammendrag
Effekten av detomidin på den elektriska aktiviteten i livmodern undersöktes under den sista trimestern hos 6 dräktiga ston.
Effekten observerades 3–5 min efter i.m, injektion, och den kvarstod i 50–70 min. Doser av 20 och 40 μg/kg kroppsvikt minskade den elektriska aktiviteten i myometriet, medan en dos av 60 μg/kg inte hade någon effekt på aktiviteten.
På basen av dessa resultat kan man utgå ifrån att doser av 20, 40 och 60 μg/kg detomidin /kg kroppsvikt kan ges åt ston under den sista dräktig-hetstrimestem utan risk för abort inducerad av en ökad elektrisk aktivitet i livmodern.
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