Table 4.
Top 10 DMRs for differential methylation between sexes in (A) adult lung tissue and (B) foetal lung tissue
| Chr: Position | Width (bp) | No. of CpGs | Stouffer P | Mean difference | UCSC gene |
|---|---|---|---|---|---|
| Chr11: 59,317,890–59,318,777 | 888 | 5 | 4.47E-34 | −0.0245 | SNORD43 |
| Chr6: 127,796,287–127,797,286 | 1000 | 7 | 2.94E-30 | −0.0802 | SNORA8, SNORD28, SOGA3, SNORA20 |
| Chr6: 49,681,178–49,681,774 | 597 | 9 | 2.66E-23 | −0.0902 | SNORA38, SNORA8, SCARNA15, CRISP2, SNORA20 |
| Chr6: 74,063,522–74,064,594 | 1073 | 8 | 2.06E-19 | −0.0734 | SNORA38, SNORA8, SCARNA15, SNORD28, DPPA5, SNORA20 |
| Chr1: 75,590,483–75,591,353 | 871 | 5 | 6.15E-14 | −0.1013 | snoU13, Y_RNA, SCARNA16, U1, SCARNA18, SNORD112, SNORA63, SNORD46, SNORA2, SNORD81, U3, SNORA51, SNORA25, SNORD64, ACA64, SNORD78, snoU109, SNORD60, SNORD116 |
| Chr7: 157,405,965–157,406,737 | 773 | 5 | 3.41E-13 | 0.0946 | AC005481.5, PTPRN2 |
| Chr12: 53,084,709–53,085,323 | 615 | 4 | 2.42E-11 | −0.0144 | KRT77, snoMe28S-Am2634 |
| Chr10: 124,638,200–124,639,892 | 1693 | 18 | 3.02E-11 | −0.0332 | RP11-564D11.3, CUZD1, FAM24B |
| Chr6: 74,103,959–74,104,868 | 910 | 8 | 8.53E-11 | −0.0652 | SNOR, A38, SNORA8, SCARNA15, DDX43, SNORD28, OOEP, SNORA20 |
| Chr17: 38,023,679–38,024,636 | 958 | 5 | 1.88E-10 | −0.0601 | SNORA69, ZPBP2 |
| Chr: Position | Width (bp) | No. of CpGs | Stouffer P | Mean difference | UCSC gene |
| Chr17: 38,023,480–38,024,636 | 1157 | 6 | 1.15E-27 | −0.0816 | SNORA69, ZPBP2 |
| Chr8: 120,684,721–120,685,686 | 966 | 10 | 3.26E-15 | −0.0403 | ENPP2 |
| Chr6: 127,796,287–127,797,286 | 1000 | 7 | 1.75E-14 | −0.0590 | SNORA8, SNORD28, SOGA3, SNORA20 |
| Chr5: 23,506,735–23,507,656 | 919 | 9 | 3.18E-14 | −0.0792 | PRDM9, SNORA27, SNORA68, RP23P5, 7SK, SNORD45 |
| Chr1: 156,393,461–156,394,727 | 1267 | 3 | 9.76E-13 | −0.0918 | snoU13, Y_RNA, SCARNA16, SCARNA16, SNORD112, SNORA63, U3, SNORD51, SNORA25, SNORD59, SCARNA20, SNORA67, U6, SNORA77, SNORA26, SNORA72, U9, SNORA31, SNORA40, C1orf61, SNROD64, ACA64, SNORD78, snoU109, SNORD60, SNORD116 |
| Chr17: 40,556,833–40,557,508 | 676 | 4 | 1.86E-12 | −0.0713 | SNORA69, PTRF |
| Chr2: 213,696,794–213,698,158 | 1365 | 6 | 2.48E-11 | −0.0698 | PCED1CP, SCARNA6, SNORD39, SNORA75, SNORA48, ACO79610.1 |
| Chr20: 3,051,954–3,053,196 | 1243 | 12 | 5.52E-11 | −0.0397 | OXT |
| Chr19: 58,861,502–58,862,398 | 897 | 6 | 8.81E-11 | −0.0418 | A1BG-AS1, A1BG, CTD-2619J13.8 |
| Chr8: 24,800,824–24,800,883 | 60 | 2 | 4.79E-10 | −0.1032 | SNORA7 |