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. 2021 Apr 23;13(5):614. doi: 10.3390/pharmaceutics13050614

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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In vitro study using liposome and EVL-loaded liposome. Cell viability of (A) liposome and (B) EVL-loaded liposome. (C) Confocal images for interaction between DiR-labeled liposome and HCASMCs. The lysosome and nucleus of HCASMCs were stained by lysotracker (green) and Hoechst (blue), respectively (Scale bars equal to 40 μm). Values are presented as mean ± SD (n = 3) and statistical significance was obtained with one-way analysis of ANOVA with Tukey’s multiple comparison post-test (* p < 0.05; ** p < 0.01; *** p < 0.001). HCASMCs: Human Coronary Artery Smooth Muscle Cells.