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. 2021 Apr 30;10(5):1072. doi: 10.3390/cells10051072

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Functional association network for ELISA-detected secreted factors. Using the online tool STRING, protein–protein interaction levels for 58 proteins of the ASC secretome after OA-SF treatment were mined. Legend: factors involved in Extracellular matrix organization, red nodes; Immune response, purple nodes; Inflammatory response, blue nodes; Cell migration, green nodes; Cell chemotaxis, yellow nodes. Edges represent protein–protein associations, with thickness representing Edge confidence (medium: 0.400, high: 0.700, highest: 0.900). Empty nodes: proteins of unknown 3D structure; filled nodes: some 3D structure is known or predicted.