Table 1.
Selective autophagy and viruses.
| Selective Autophagy (SA) |
Targeted Cargos | SA Receptors and Associated Factors | Effects on Herpesvirus Infection |
|---|---|---|---|
| Mitophagy | Mitochondria | SLRs 1 (p62, NDP52, OPTN, NBR1, and TAX1BP1) | Proviral |
| BNIP3, NIX/BNIP3L, FUNDC1, PHB2 | |||
| Aggrephagy | Aggregated proteins | SLRs (p62 and NBR1) | Proviral |
| TOLLIP, TBC1d5 | |||
| Nucleophagy | Nuclei | SLRs (p62) | Proviral |
| Ferritinophagy | Ferritin | NCOA4 | Antiviral |
| Xenophagy/Virophagy (viruses) |
Intracellular viruses | SLRs (p62) STING, TRIM23, TBK1, FANCA/FANCC |
Antiviral |
| Xenophagy (bacteria) |
Intracellular bacteria | SLRs (p62, NDP52, and OPTN) | |
| Reticulophagy | Endoplasmic reticulum |
RETREG1/FAM134B | |
| Pexophagy | Peroxisomes | SLRs (p62 and NBR1) | |
| Ribophagy | Ribosomes | NUFIP1 | |
| Lipophagy | Lipids (Lipid drops) | AUP1 | |
| Lysophagy | Lysosomes | SLRs (p62) | |
| Glycophagy | Glycogen | STBD1 | |
| DN- and RN-autophagy | Nucleic acids | LAMP2C, SIDT2 |
1 SLRs: Sequestosome-like receptors.