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. 2021 May 10;10(5):576. doi: 10.3390/pathogens10050576

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Phylogenetic analysis of partial enteroviral 5′-UTR sequences (410 bp). The tree was constructed using enteroviral sequences obtained from children in five schools and nurseries as follows: school 1 (blue), school 2 (green), school 3 (yellow), school 4 (red), and school 5 (gray). The maximum likelihood method with a bootstrap value of 1000 was applied. Sample names and nucleotide sequence accession numbers are marked with symbols as follows: filled circles, sequences from HFMD cases; filled squares, sequences from cases with herpangina; open triangles, sequences from asymptomatic contact cases. Bootstrap values ≥ 50 are displayed at the nodes. The bar represents nucleotide substitutions per site. A porcine enterovirus sequence served as an out-group.