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. 2021 May 11;10(5):1164. doi: 10.3390/cells10051164

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Tom20 and Tom70 Interactions. (A) Structure of human Tom70 bound to SARS-CoV-2 protein Orf9b. (left) Human Tom70 (yellow) binding pocket with Orf9b (red) bound. (middle) Closer view of Orf9b binding pocket with hTom70 (yellow) and Orf9b (red). (right) Superimposition of human Tom70 (yellow), yeast Tom70 (cyan) and yeast Tom71 (brick red). Superimposition highlights the rotation of the N-terminal domain between the fungal structures. (B) Tom70 and Tom20 interactions as described. Distances do not represent interaction strength.