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. 2021 May 10;10(5):1149. doi: 10.3390/cells10051149

Table 4.

Odds ratios (ORs) of CTCs, CEA, CA19-9, CTC clusters and their combination to predict recurrence of patients with stage III CRC. N/A: not analyzable due to absence of recurrent.

Stage III CRC (51 Cases) No. of Cases
Recurrence No Recurrence Recurrence Rate (Odds Ratio, OR)
CTCs > 3 6 4 28.6% 2.6
CTCs ≤ 3 15 26 13.3%
CEA > 5 8 18 30.8% 5.1
CEA ≤ 5 2 23 8%
CA19-9 > 37 4 4 50% 6.2
CA19-9 ≤ 37 6 37 14%
With CTC clusters 4 7 36.4% 3.2
Without CTC clusters 6 34 15%
CTCs > 3; CEA > 5 6 7 46.2% 7.3
Others 4 34 10.5%
CTCs > 3; CA19-9 > 37 2 0 100% N/A
Others 8 41 16.3%
CTCs > 3; With CTC clusters 3 2 60% 8.4
Others 7 39 15.2%
CEA > 5; CA19-9 > 37 3 3 50% 5.4
Others 7 38 15.6%
CEA > 5; With CTC clusters 4 5 44.4% 4.8
Others 6 36 14.3%
CA19-9 > 37; With CTC clusters 3 3 50% 5.4
Others 7 38 15.6%
CTCs > 3; CEA > 5; CA19-9 > 37 2 0 100% N/A
Others 8 41 16.3%
CTCs > 3; CEA > 5; With CTC clusters 3 1 75% 17.1
Others 7 40 14.9%
CTCs > 3; CA19-9 > 37; With CTC clusters 2 0 100% N/A
Others 8 41 16.3%
CEA > 5; CA19-9 > 37; With CTC clusters 3 3 50% 5.4
Others 7 38 15.6%
CTCs > 3; CEA > 5;
CA19-9 > 37; With CTC clusters
2 0 100% N/A
Others 8 41 16.3%