Figure 15.

Histamine treatment of P. falciparum NF54 in vitro had no significant direct effects on parasite growth. Left: percent of parasitemias at 48 h (one growth cycle) following treatment with 1, 10, and 100 nM histamine (hist), an equivalent volume of water used to deliver histamine treatments or only media added to parasites. Human RBCs were included to indicate the specificity of flow cytometric detection of fluorescence. Right panel: parasites from the left panel at 96 h after treatment. N = 4 replicates analyzed per treatment, and each analyzed in duplicate; ANOVA (α = 0.05).