Table 3.
Etest MIC values of germinated B. anthracis spores at various time points.
| Incubation Duration (h) | MIC (µg/mL) | |||||||
|---|---|---|---|---|---|---|---|---|
| CIP | DOX | AMP | CHL | CLI | CLA | VAN | RIF | |
| 6 | 0.06 | <0.016 | 0.03-0.06 | 4–8 | 0.125–0.5 | 0.25–0.5 | 0.125 | 0.03–0.06 |
| 8 | 0.06 | ≤0.016 | 0.03–0.06 | 4–8 | 0.125–0.5 | 0.25–0.5 | 0.25 | 0.03–0.125 |
| 10 | 0.06 | ≤0.016 | 0.06 | 4–8 | 0.25 | 0.25 | 0.25 | 0.06 |
| 16 | 0.06 | 0.016–0.06 | 0.06–0.125 | 4 | 0.25–0.5 | 0.25 | 1 | 0.25–0.5 |
| 18 | 0.06 | 0.016–0.125 | 0.06–0.125 | 4–8 | 0.25–0.5 | 0.25 | 1–2 | 0.25–0.5 |
| 20 | 0.06 | 0.06–0.125 | 0.06–0.125 | 4–8 | 0.25–0.5 | 0.25 | 1–2 | 0.5 |
| 23 | 0.06 | 0.06–0.125 | 0.06–0.125 | 8 | 0.25–0.5 | 0.25–0.5 | 1–2 | 0.25–0.5 |
CIP—ciprofloxacin; DOX—doxycycline; AMP—ampicillin; CHL—chloramphenicol; CLI—clindamycin; CLA—clarithromycin; VAN—vancomycin; RIF—rifampicin; the MIC values were determined by at least three independent assays.