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. Author manuscript; available in PMC: 2021 May 27.
Published in final edited form as: Hepatology. 2020 Oct 22;72(6):2077–2089. doi: 10.1002/hep.31212

FIG. 3.

FIG. 3.

Effects of G-1 on bile flow rates (A) as well as hepatic output of biliary cholesterol (B), phospholipids (C), and bile salts (D) during the first hour of biliary secretion in OVX wild-type, GPR30−/−, and ERα−/− mice treated with G-1 at 0 or 1 μg/day and fed the lithogenic diet for 8 weeks. #P < 0.05 compared to OVX wild-type mice receiving no G-1 and fed the lithogenic diet for 8 weeks; *P < 0.05 compared to OVX wild-type mice treated with G-1 at 1 μg/day and fed the lithogenic diet for 8 weeks. Abbreviation: B.W., body weight.