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. 2021 Apr 20;96(16):e2078–e2089. doi: 10.1212/WNL.0000000000011792

Figure 1. Anatomical and Somatosensory Localization of Pathophysiology in Chronic Immune Sensory Polyradiculopathy (CISP) and CISP-Plus.

Figure 1

(A) Anatomical pictorial representation of the nerves affected in (A.a) CISP (isolated sensory root involvement) and in (A.b) CISP-plus (primarily but not solely sensory root involvement). The dark shaded area represents the dorsal root where the primary pathology occurs in both conditions and the dotted area represents lesser involvement of other nerves (shown are ventral root, dorsal root ganglion, and spinal nerve) that occurs in CISP-plus but not in CISP. (B) Median nerve somatosensory evoked potential (SSEP) tracings from patients with CISP (B.a) and patients with CISP-plus (B.b) show examples where slowing occurs before the cervical spine site (N13) and within the segment between the clavicular and cervical spine sites (N9–N13, the segment containing the sensory root). The absolute and interpeak latencies values (in milliseconds) from the median SSEP studies as well as the normal values are listed at the bottom. These SSEP findings show that the slowing in both conditions primarily occurs at the sensory root level.