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The Journal of Biological Chemistry logoLink to The Journal of Biological Chemistry
. 2021 May 22;296:100757. doi: 10.1016/j.jbc.2021.100757

Withdrawal: Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation

Qiuyan Liu, Qinchun Tan, Yuanyuan Zheng, Kun Chen, Cheng Qian, Nan Li, Qingqing Wang, Xuetao Cao
PMCID: PMC8166908  PMID: 34237884

VOLUME 289 (2014), PAGES 11522–11535

This article has been withdrawn by the authors. The Journal states that lanes 1 and 2 in the Fas panel immunoblot in Fig. 1A were reused in lanes 2 and 3 of Fas panel immunoblot in Fig. 1C. Lanes 2 and 3 in GAPDH panel immunoblot in Fig. 1A were reused in lanes 1 and 2 of GAPDH panel immunoblot in Fig. 1C. In Fig. 6D, lanes 2 to 4 were duplicated in lanes 5 to 7 of the Nu65 immunoblot. The authors are able to retrieve all raw data and offer to update the respected panels using the same raw images again or those from experiments under the same conditions. The offer was declined by the Journal. The authors state that the above issues do not affect the interpretation of the data nor conclusions of this research study. The authors state that the activation of NF-κB signal pathways by Fas signaling reported in this article has been confirmed in breast cancer and other types of cancer by other independent studies. The authors have indicated that they plan to submit this work elsewhere for publication.


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