Skip to main content
. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Gastroenterology. 2021 Mar 4;160(7):2483–2495.e26. doi: 10.1053/j.gastro.2021.02.061

Figure 1. Single-SNP association analysis results.

Figure 1.

A) Manhattan plots showing the associations of chrX SNPs with PBC in the analyzed cohorts (CA, Canadians; ITA, Italians; UK, British; JP, Japanese; CH, Chinese) for the Stouffer analysis (Test 2). The blue line represents the P=1*10−5 significance level. SNPs showing lowest P values are indicated by an arrow.

B) Venn diagrams show the number of genes mapping in correspondence/proximity of SNPs at P<0.0005 for each population. Chinese and Japanese show the major number of overlapping signals (genes are listed); the only gene shared by three populations is also highlighted.