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. 2021 May 20;12:692761. doi: 10.3389/fphys.2021.692761

Corrigendum: Angiotensin Converting Enzyme 2 (ACE2) in Pregnancy: Preeclampsia and Small for Gestational Age

Sonia Tamanna 1,2,3, Vicki L Clifton 4,5, Kym Rae 5, Dirk F van Helden 2, Eugenie R Lumbers 1,2,3, Kirsty G Pringle 1,2,3,*
PMCID: PMC8173707  PMID: 34093245

In the original article, there was a mistake in Figure 3A and G as published. In Figure 3A it was written P=0<.001 instead of P<0.001 and Figure 3G it was written P=0.0012 instead of P=0.012. The corrected Figure 3 appears below.

Figure 3.

Figure 3

Plasma levels and activity of ACE, ACE2, and NEP in non-pregnant (NP) and pregnant women (A–D). Plasma levels of Ang-(1-7) were measured by radioimmunoassay in NP and pregnant women (E). Plasma ACE2/ACE ratio and ACE2 activity/ACE ratio in NP and pregnant women (F,G). Data are expressed as median and interquartile range. n = 9–10 samples for the NP group (black box), n = 7–35 samples/group for 13, 18, 30, and 36 weeks of normal pregnancy (white box). P-values were calculated using a Kruskal–Wallis test (with Dunn's multiple comparison test). *P < 0.05, **P < 0.01, ***P < 0.001 versus NP.

In the original article, there was an error. In the results section, one of the P-values was stated incorrectly.

A correction has been made to Results, ACE, ACE2, NEP, and ANG-(1-7) levels, ACE2 activity, and the ACE2/ACE ratio in women with preeclampsia, paragraph 2:

Figure 5E shows the plasma Ang-(1-7) levels in women with normal pregnancies and women with PE. Women with PE had reduced levels of plasma Ang-(1-7) compared with levels in women with normal pregnancies (P = 0.034; Figure 5E). The ACE2/ACE ratio was increased in PE compared with normal pregnancies (P < 0.001; Figure 5F).”

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.


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