Skip to main content
Annals of Pediatric Cardiology logoLink to Annals of Pediatric Cardiology
letter
. 2021 Apr 16;14(2):249–250. doi: 10.4103/apc.apc_38_21

Response from the authors to the letter to editor (MVR in infants)

Hitendu Dave 1
PMCID: PMC8174639  PMID: 34103875

Sir,

We read with interest, the letter to the editor discussing our recent article on Melody valve implantation in the mitral position. We thank the authors of “the letter to the editor” for bringing out very pertinent issues complementing and enriching our paper.[1]

We agree that pulmonary autograft or the Ross II procedure using pulmonary autograft in mitral position[2] is an important alternative which should have been included in the discussion. However, despite the seeming advantages, the experience with this procedure over the last two decades has been sporadic with reports limited to small series, at the most. This procedure is certainly loaded with the same debate as the Ross Procedure itself, of converting a single valve disease into a potentially double valve disease. This has been brought to light by the report advising caution.[3]

The other option of using an aortic or pulmonary (homovital) homograft in a Ross II fashion, is certainly worth consideration. However, vagaries of availability of a small-sized semilunar valve, need to order a predetermined size from a distant homograft bank and the question marks about the longevity of these homografts, mean that this option is not always practicable. The concept of homovital tissue, to our knowledge, has not stood the scrutiny of time, since recent developments profess the use of decellularized homografts[4] to improve durability.

To summarize, while the Ross II concept using either an autograft, homograft or a decellularized homograft is certainly important, the use of a stented Melody valve adds to the armamentarium of available alternatives, till a unique alternative with overwhelming advantages emerges.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

REFERENCES

  • 1.Dranseika V, Prêtre R, Kretschmar O, Dave H. Melody valve to replace the mitral valve in small children: Lessons learned. Ann Pediatr Card. 2021;14:35–41. doi: 10.4103/apc.APC_74_20. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Kumar AS, Aggarwal S, Choudhary SK. Mitral valve replacement with the pulmonary autograft; The Ross II Procedure. J Thorac Cardiovasc Surg. 2001;122:378–9. doi: 10.1067/mtc.2001.114095. [DOI] [PubMed] [Google Scholar]
  • 3.Talwar S, Sinha P, Moulick A, Jonas R. Mitral valve replacement with the pulmonary autograft in children: A word of caution. Pediatr Cardiol. 2009;30:831–3. doi: 10.1007/s00246-009-9431-4. [DOI] [PubMed] [Google Scholar]
  • 4.Horke A, Bobylev D, Avsar M, Meyns B, Rega F, Hazekamp M, et al. Paediatric aortic valve replacement using decellularized allografts. Eur J Cardiothorac Surg. 2020;58:817–24. doi: 10.1093/ejcts/ezaa119. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Annals of Pediatric Cardiology are provided here courtesy of Wolters Kluwer -- Medknow Publications

RESOURCES