Abstract
In an attempt to further elucidate the causes of perinatal mortality in pigs, a histomorphological study of organs from normal 0.4 to 60 h old euthanized piglets and from perinatal dead/euthanized pigs belonging to different mortality groups was performed. The heart, lung, liver, kidney, spleen, thymus, pancreas, thyroid and adrenal glands were studied; all sections were examined without previous knowledge of the cause of death. Different observations in the organs were judged according to a scale of 1 to 4 where 1 = none or significant and 4 = a high degree of specific organ characteristics. The percentage of the group examined that scored 3–4 was calculated for each organ characteristic, and with the help of covariance analysis adjusted for the linear effect of total body weight (at the time of death), age, gestation length, and litter size (all pigs born, alive or dead). This first report describes the observations for the euthanized normal animals.
Keywords: histomorphological characteristics, organs, perinatal period.
Sammanfattning
I strävan att söka finna orsaker till perinatal dödlighet hos svin utfördes en histomorfologisk studie av organ från 0,4–60 timmar gamla avlivade normala grisar och från lika gamla perinatalt döda eller sjuka, dödade djur tillhörande olika mortalitetsgrupper. Hjärta, lunga, lever, njure, mjälte, thymus, pankreas, thyreoidea och binjurer studerades. Alla histologiska snitt undersöktes utan vetskap om respektive djurs dödsorsak. Graden av varierande observationer i organen noterades enligt en skala 1 till 4 där 1 angav ingen eller obetydlig och 4 höggradig förekomst av respektive iakttagelser. Procenten organobservationer graderade 3–4 inom de studerade grupperna djur fastställdes och justerades med hjälp av kovariansanalys för den liniära effekten av total kroppsvikt (vid dödstillfallet) ålder, dräktighetslängd, kullstorlek (alla födda grisar, levande eller döda). Denna första rapport beskriver iakttagelser hos avlivade normala djur.
Full Text
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Acknowledgement
This work was supported by Grant Nos. P111 och P139 from the Swedish University of Agricultural Sciences (J. Svendsen) and by Grant No. 6000 1–5 from the National Veterinary Institute (N.-E. Björklund).
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