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. 1987 Jun 1;28(2):143–149. doi: 10.1186/BF03548234

Fat Infiltration in the Liver of Finnish Ayrshire Cows during Early Lactation

Fettinfiltration i levern hos finska Ayrshire kor under tidig laktation

Y Gröhn 1, K Heinonen 1, L-A Lindberg 1,✉
PMCID: PMC8185756  PMID: 3447469

Abstract

The incidence and severity of fat infiltration in the liver of Finnish Ayrshire cows at 1 and 8 weeks after calving were studied. All multiparous (n = 88) and some primiparous (n = 17) cows that calved in 20 commercial milk recorded herds were investigated. The cows lost weight and a condition score decreased significantly (p < 0.05) during early lactation. Blood samples were taken at 1, 4 and 8 weeks after calving. Ketone body concentrations were highest at 4 weeks after calving. Albumin and total protein concentrations and ornithine carbamyltransferase activity in the blood increased significantly (p = < 0.05) from 1 to 8 weeks after calving. The percentage of liver fat (v/v) was significantly (p < 0.05) greater at 1 (3.9 ± 0.5 %) than at 8 weeks (1.2 ± 0.3 %) after calving. Eighty-nine of 102 cows had less than or equal to 9 % of fat in the liver (mean 2.3 ± 0.2 %), and 13 cows had more than 9% (mean 14.9 ± 1.2%) at 1 week after calving. Only blood acetoacetate and plasma aspartate aminotransferase differed significantly between the groups. In the fatty liver group the incidence rate of treated cases of ketosis was 30.8 ± 13.3 % and of parturient paresis 23.1 ± 12.2 %. In the non-fatty liver group the rates were 10.1 ± 3.2 % and 7.8 ± 2.9 %, respectively. The differences were not significant.

Keywords: fatty liver, bovine, parturition

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Acknowledgements

This study was supported by the Medical Research Council of the Academy of Finland. The authors thank Mrs. Riikka Santalahti and Mrs. Tuire Pankasalo for skilful technical assistance.

References

  1. Committee on enzymes of the Scandinavian Society for Clinical ChemistryClinical Physiology. Scand. J. clin. Lab. Invest. 1974;33:291–306. doi: 10.3109/00365517409082499. [DOI] [Google Scholar]
  2. Dixon WJ. BMPD Statistical Software. Berkeley: University of California Press; 1981. [Google Scholar]
  3. Dixon WJ, Massey FJ. Introduction to Statistical Analysis. New York, NY: McGraw - Hill Book Co.; 1969. [Google Scholar]
  4. Doumas BT, Watson W, Biggs HG. Albumin standards and the measurement of serum albumin with bromcresol green. Clin. Chim. Acta. 1971;31:87–96. doi: 10.1016/0009-8981(71)90365-2. [DOI] [PubMed] [Google Scholar]
  5. Gerlach U, Hiby W. Methods of Enzymatic Analysis. New York: Academic Press; 1974. pp. 569–573. [Google Scholar]
  6. Gröhn Y. Propionate loading test for liver function in spontaneously ketotic cows. Res. Vet. Sci. 1985;39:24–28. doi: 10.1016/S0034-5288(18)31764-8. [DOI] [PubMed] [Google Scholar]
  7. Gröhn Y, Lindberg L-A. Methodological aspects of the microscopy of bovine liver biopsies. J. comp. Path. 1982;92:567–577. doi: 10.1016/0021-9975(82)90009-3. [DOI] [PubMed] [Google Scholar]
  8. Gröhn Y, Lindberg L-A, Bruss ML, Farver TB. Fatty infiltration of the liver in spontaneously ketotic dairy cows. J. Dairy Sei. 1983;66:2320–2328. doi: 10.3168/jds.S0022-0302(83)82088-8. [DOI] [PubMed] [Google Scholar]
  9. Gröhn Y, Saloniemi H, Syväjärvi J. An epidemiological and genetic study on registered diseases in Finnish Ayrshire cattle. I. The data, disease occurrence and culling. Acta vet. scand. 1986;27:182–195. doi: 10.1186/BF03548163. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Gröhn Y, Thompson JR, Bruss L. Epidemiology and genetic basis of ketosis in Finnish Ayrshire cattle. Prev. Vet. Med. 1984;3:65–77. doi: 10.1016/0167-5877(84)90025-4. [DOI] [Google Scholar]
  11. Jacobsen LK. Quantitative determination of blood glucose using glucose oxidase and peroxidase. Scand. J. clin. Lab. Invest. 1960;12:76–79. doi: 10.3109/00365516009046170. [DOI] [PubMed] [Google Scholar]
  12. Ministry of Agriculture, FisheriesFood . Condition Scoring of Dairy Cows. 1978. [Google Scholar]
  13. Morrow DA, Hillman D, Dade AW, Kitchen H. Clinical investigation of a dairy herd with fat cow syndrome. J. Amer. vet. med. Ass. 1979;174:161–167. [PubMed] [Google Scholar]
  14. Ohshita MH, Takeda Y, Ozawa K, Honjo I. A direct method for the estimation of ornithine carbamyltransferase activity in serum. Clin. Chim. Acta. 1976;67:145–152. doi: 10.1016/0009-8981(76)90253-9. [DOI] [PubMed] [Google Scholar]
  15. Reid IM. Incidence and severity of fatty liver in dairy cows. Vet. Rec. 1980;107:281–284. doi: 10.1136/vr.107.12.281. [DOI] [PubMed] [Google Scholar]
  16. Reid IM, Collins RA. The pathology of postparturient fatty liver in high-yielding dairy cows. Invest. Cell Pathol. 1980;3:237–249. [PubMed] [Google Scholar]
  17. Reid IM, Roberts CJ. Subclinical fatty liver in dairy cows. Current research and future prospects. Irish vet. J. 1983;37:104–110. [Google Scholar]
  18. Roberts CJ, Reid IM, Rowlands GJ, Patterson A. A fat mobilization syndrome in dairy cows in early lactation. Vet. Rec. 1981;108:7–9. doi: 10.1136/vr.108.1.7. [DOI] [PubMed] [Google Scholar]
  19. Sommer H. Präventive Medizin bei Milchkühen. (Preventive medicine for dairy cows) Vet. Med. Rew. 1975;1:41–61. [Google Scholar]
  20. Työppönen J, Kauppinen K. The stability and automatic determination of ketone bodies in blood samples taken in field conditions. Acta vet. scand. 1980;21:55–61. doi: 10.1186/BF03546900. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Weichselbaum TE. Determination of protein in blood, serum and plasma. Amer. J. clin. Pathol. 1946;16:40–52. doi: 10.1093/ajcp/16.3_ts.40. [DOI] [PubMed] [Google Scholar]

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