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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Stroke. 2021 May 18;52(6):e263–e265. doi: 10.1161/STROKEAHA.121.034995

Table.

Ongoing trials comparing blood pressure management protocols after successful reperfusion with endovascular therapy

Name Identifier* Location SBP target (mmHg) by group Primary outcomes Estimated year of completion
Experimental Control
Second Enhanced Control of Hypertension and Thrombectomy Stroke Study (ENCHANTED2) NCT04140110 China <120 ** 140–180 shift in mRS scores at 90 days 2023
Outcome in Patients Treated With Intraarterial Thrombectomy - optiMAL Blood Pressure Control (OPTIMAL-BP) NCT04205305 South Korea <140 ** <180 -mRS 0–2 at 90 days
-symptomatic intracerebral hemorrhage
-death at 90 days
2024
Blood Pressure After Endovascular Stroke Therapy-II (BEST-II) NCT04116112 USA −<160 **
−<140 **
<180 Final infarct volume
Utility-weighted mRS at 90 days
2023

mRS denotes modified Rankin scale, SBP systolic blood pressure

**

To be achieved within 60 minutes of randomization