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Oxford University Press - PMC COVID-19 Collection logoLink to Oxford University Press - PMC COVID-19 Collection
. 2021 May 14:ciab436. doi: 10.1093/cid/ciab436

Evaluating the Presence of Replication-Competent SARS-CoV-2 from Nursing Home Residents with Persistently Positive RT-PCR Results

Joseph D Lutgring 1,, Farrell A Tobolowsky 1,2, Kelly M Hatfield 1, Nicholas B Lehnertz 3, Maureen M Sullivan 3, Karen G Martin 3, Amelia Keaton 4, D Joseph Sexton 1, Azaibi Tamin 1, Jennifer L Harcourt 1, Natalie J Thornburg 1, Sujan C Reddy 1, John A Jernigan 1
PMCID: PMC8194652  PMID: 33988220

Abstract

Replication-competent virus has not been detected in individuals with mild to moderate COVID-19 more than 10 days after symptom onset. It is unknown whether these findings apply to nursing home residents. Of 273 specimens collected from nursing home residents >10 days from the initial positive test, none were culture positive.

Keywords: COVID-19, SARS-CoV-2, viral culture, nursing home, RT-PCR


Articles from Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America are provided here courtesy of Oxford University Press

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