Table 4.
Variables |
Controls: CCA IMT (n = 60) |
All SLE: CCA IMT (n = 60) |
||||||
---|---|---|---|---|---|---|---|---|
Right CCA |
Left CCA |
Right CCA |
Left CCA |
|||||
B | P | B | P | B | P | B | P | |
Age | 7.95 | 0.014 | 2.78 | 0.37 | 0.01 | 0.91 | 0.14 | 0.26 |
Female gender | –110.64 | 0.36 | 72.60 | 0.51 | –2.83 | 0.48 | –5.14 | 0.20 |
Duration of SLE | 0 | 0 | 0 | 0 | 0.15 | 0.31 | 0.35 | 0.02 |
SDI score | 0 | 0 | 0 | 0 | 0.35 | 0.77 | 3.07 | 0.01 |
SLEDAI-2K | 0 | 0 | 0 | 0 | 0.30 | 0.65 | 0.04 | 0.95 |
Traditional risk factors and laboratory data | ||||||||
BMI (kg/m2) | 11.6 | 0.30 | 16.42 | 0.12 | –0.16 | 0.64 | –0.30 | 0.37 |
Ever smoker (former or current) | 0 | 0 | 0 | 0 | –1.05 | 0.74 | –1.10 | 0.74 |
Systolic blood pressure | 8.60 | 0.002 | 3.03 | 0.26 | –0.03 | 0.76 | 0.10 | 0.25 |
Diastolic blood pressure | 11.22 | 0.014 | 2.75 | 0.53 | –0.01 | 0.95 | 0.19 | 0.16 |
Raynaud | –105.00 | 0.32 | –149.94 | 0.11 | –0.87 | 0.78 | 0.58 | 0.85 |
Estimated glomerular filtration rate | 0 | 0 | 0 | 0 | –0.04 | 0.68 | 0.10 | 0.25 |
Total cholesterol | 21.21 | 0.53 | 34.38 | 0.27 | 1.37 | 0.32 | 3.07 | 0.03 |
High-density lipoprotein (HDL) | 138.84 | 0.14 | 5.24 | 0.95 | 0.02 | 1.00 | 5.83 | 0.07 |
Low-density lipoprotein (LDL) | 3.10 | 0.94 | 51.04 | 0.17 | 0.06 | 0.52 | 1.18 | 0.48 |
Triglycerides (TG) | 19.14 | 0.77 | –17.60 | 0.77 | 3.10 | 0.09 | 4.81 | 0.01 |
High-sensitivity CRP | –9.26 | 0.40 | –6.30 | 0.53 | –0.10 | 0.84 | 0.26 | 0.59 |
Medical treatment, ongoing | ||||||||
Antimalarial agents | 0 | 0 | 0 | 0 | –5.98 | 0.18 | –2.56 | 0.58 |
Glucocorticoid therapy | 0 | 0 | 0 | 0 | –3.80 | 0.16 | –0.10 | 0.70 |
Warfarin therapy | 0 | 0 | 0 | 0 | –1.55 | 0.66 | –1.36 | 0.70 |
Antiplatelet therapy | 0 | 0 | 0 | 0 | –5.34 | 0.12 | 2.76 | 0.44 |
Statin therapy | 0 | 0 | 0 | 0 | –4.42 | 0.37 | –4.80 | 0.34 |
DMARD therapy | 0 | 0 | 0 | 0 | 1.60 | 0.55 | 3.75 | 0.17 |
APS: Antiphospholipid syndrome; CRP: C-reactive protein; BMI: body mass index; DMARDs: disease modifying anti-rheumatic drugs; LN: lupus nephritis; SDI: SLICC/ACR damage index; SLE: systemic lupus erythematosus.
Notes: Statistically significant associations shown in bold.