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CYP1A1/1B1 gene expression in HCT116. (A) Cells were treated with TNF-α dose range of (0.01-100 pg/mL) over 72 h. (B) cells co- treated with BaP and PhIP. Gene expression were measured by RT-qPCR. Data are shown as fold change. Significance was calculated using one-way ANOVA with a Dunnett test (GraphPad Prism 8). The data are presented as SEM from three independent cultures.
