A. Rotarod performance of mice at 16 weeks, two weeks after the start of treatment (WT aCSF (N=15), WT BDNF (N=10), ATXN1[82Q] aCSF (N=12), and ATXN1[82Q] BDNF (N=16). B. Rotorod performance of mice at 19 weeks, one week after the cessation of treatment (ATXN1[82Q] aCSF, N=11, ATXN1[82Q] BDNF, N=15). Each data point represent individual mouse, bars show the average with error bars = SEM. * P<0.05, one-way ANOVA with post hoc Sidak’s test.