(A) Sampling localities of wild-caught mice used to establish inbred lines in this study (map obtained from Google satelites.pro): Edmonton, Canada (EDM), Tucson, AZ (TUC), Gainesville, FL (GAI), Saratoga Springs, NY (SAR), and Manaus, Brazil (MAN). (B) Relative water consumption (g water consumed/ g mouse) in descendants of mice from different localities. Lines indicate comparisons that are significant (p < 0.05; Mann-Whitney U tests). Vertical lines denote 1.5x the interquartile range.