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. 2011 Apr 7;26(2):73. doi: 10.1007/s12250-011-3186-9

Laboratory detection and diagnosis of filoviruses

Yun-peng Wang 1, Xian-en Zhang 1, Hong-ping Wei 1,✉
PMCID: PMC8222480  PMID: 21468930

Abstract

Ebola virus (EBOV) and Marburg virus (MARV), belonging to the Filoviridae family, emerged four decades ago and caused severe viral hemorrhagic fever in human and other primates. As high as 50–90% mortality, filoviruses can cause significant threats to public health. However, so far no specific and efficient vaccine has been available, nor have other treatment methods proved to be effective. It is of great importance to detect these pathogens specific, rapidly and sensitively in order to control future filovirus outbreaks. Here, recent progresses in the development of detection and diagnosis methods for EBOV and MARV are summarized.

Key words: Filovirus, Ebola virus (EBOV), Marburg virus (MARV), Enzyme-linked immunosorbent assay (ELISA), Polymerase chain reaction (PCR)

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Articles from Virologica Sinica are provided here courtesy of Wuhan Institute of Virology, Chinese Academy of Sciences

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