Table 5.

Multivariable logistic regression model for preterm birth (n=1000)

	Univariable analyses			Multivariable analyses
	OR	95% CI	P value	aOR	95% CI	P value
Anti-TNF-α monotherapy	0.84	0.46 to 1.51	0.55	0.84	0.44 to 1.26	0.61
Thiopurine monotherapy	1.26	0.82 to 1.94	0.29	1.16	0.71 to 1.88	0.55
Anti-TNF-α and thiopurine	1.54	0.76 to 3.12	0.23	1.43	0.66 to 3.12	0.37
Systemic corticosteroids	2.81	1.81 to 4.35	<0.01	2.62	1.56 to 4.38	<0.01
Disease activity	1.61	1.06 to 2.46	0.02	1.06	0.61 to 1.89	1.83
IBD type (CD or UC/IBDU)	0.81	0.57 to 1.17	0.26
Maternal age	0.97	0.93 to 1.02	0.28
Smoking during pregnancy	0.98	0.41 to 2.35	0.96
Obstetric complications	1.35	1.22 to 1.49	<0.01	4.07	2.54 to 6.54	<0.01
Endoscopy during pregnancy	1.94	1.08 to 3.47	0.02	1.17	0.57 to 2.38	0.83

aOR, adjusted odds ratio; CD, Crohn’s disease; IBD, inflammatory bowel disease; IBDU, inflammatory bowel disease unclassified; TNF, tumour necrosis factor; UC, ulcerative colitis.