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IAV structure and conservation of HA. (A) Illustrated structure of IAVs. (B) Conservation of group 1 HA with variable epitopes (Ca1, Ca2, Cb, Sa, Sb) and conserved epitopes (RBS, lateral patch, broadly neutralizing (BN) stalk epitope, and anchor epitope) highlighted. (C) Conservation of group 2 HA with variable epitopes (A, B, C, D, E) and conserved epitopes (RBS and group 2 stalk epitope) highlighted.
