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. 2021 Jun 11;10(6):1465. doi: 10.3390/cells10061465

Table 1.

Evidence for cell–cell fusion in human cancers.

Tumor Type Normal Cells Marker Reference
breast cancer macrophages CD163, MAC387, DAP12 [59,69,73]
colon/colorectal cancer macrophages CD163, MAC387, DAP12 [68,73]
CD14, CD45, cytokeratin [20]
epithelial ovarian cancer BMDCs CD45, CXCR4 [25]
melanoma macrophages CD14, CD45, cytokeratin [20]
stromal cells BRAF (V600E) mutation [72]
BMDCs STR-analysis * [42,43]
multiple myeloma osteoclasts myeloma specific translocations [70,71,74]
non-small cell lung cancer macrophages CD14, CD45, cytokeratin, EpCAM [46]
pancreatic ductal adenocarcinoma macrophages CD45, cytokeratin [45,75]
BMDCs CD45, EpCAM, Y chromosome * [22]
renal cell carcinoma BMDCs blood group alleles *, Y-chromosome * [41,44]

* Cancer patients with a BMT history.