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. 2021 Jun 20;69:103445. doi: 10.1016/j.ebiom.2021.103445

Table 2.

Sample characteristics.

(Sub)clinical SAD (n = 39) No SAD (n = 62) Statistical analysis
Demographics
Male / Female (n) 20 / 19 31/31 χ2(1) = 0·02, p = 1·00
Generation 1 / Generation 2 (n) 19 / 20 27 / 35 χ2(1) = 0·26, p = 0·68
Age in years (mean ± SD) 30·3 ± 15·5 31·3 ± 15·2 β (± SE) = -1·0 ± 3·1, p = 0·76
Estimated IQ (mean ± SD) 104·3 ± 12·2 105·6 ± 10·5 β (± SE) = -2·1 ± 2·2, p = 0·33
Diagnostic information (n)
Clinical SAD 17 0 χ2(1) = 32·5, p < 0·001
Depressive episode present 1 1 χ2(1) = 0·15, p = 1·00
Depressive episode past 12 9 χ2(1) = 4·8, p = 0·04
Dysthymia present 3 0 χ2(1) = 5·3, p = 0·05
Dysthymia past 1 1 χ2(1) = 0·2, p = 1·00
Panic disorder lifetime 5 2 χ2(1) = 3·9, p = 0·10
Agoraphobia present 3 2 χ2(1) = 1·2, p = 0·35
Agoraphobia past 0 2 χ2(1) = 1·2, p = 0·53
Separation anxiety 0 1 χ2(1) = 0·8, p = 1·00
Specific phobia 2 3 χ2(1) = 0·02, p = 1·00
Generalized anxiety disorder present 1 0 χ2(1) = 1·7, p = 0·37
Obsessive compulsive disorder 1 0 χ2(1) = 1·7, p = 0·37
Alcohol dependency present 1 1 χ2(1) = 0·2, p = 1·00
Alcohol dependency lifetime 1 3 χ2(1) = 0·3, p = 1·00
Attention deficit hyperactivity disorder 1 3 χ2(1) = 0·3, p = 1·00
Self-report measures
Social anxiety symptoms (z-score; mean ± SD) 3·0 ± 3·3 0·6 ± 1·5 β ± SE = 2·6 ± 0·5, p < 0·001
Fear of negative evaluation (mean ± SD) 23·3 ± 12·3 12·8 ± 8·0 β ± SE = 10·4 ± 2·0, p < 0·001
Depressive symptoms (z-score; mean ± SD) 0·0 ± 0·9 -0·5 ± 0·7 β ± SE = 0·5 ± 0·2, p < 0·001
STAI - trait (mean ± SD) 38·8 ± 9·4 33·1 ± 8·5 β ± SE = 5·5 ± 1·2, p = 0·002
BIS (z-score; mean ± SD) 0·4 ± 1·3 -0·4 ± 0·9 β ± SE = 0·8 ± 0·2, p = 0·0004
BAS (z-score; mean ± SD) -0·9 ± 1·0 -0·6 ± 1·0 β ± SE = -0·5 ± 0·2, p = 0·02

aDue to technical reasons, data on the presence of subclinical SAD were lost for eight family members. Data from these participants were, however, included in the endophenotype analyses using SA-level (z-score) as a predictor. BAS = behavioral activation system; BIS = behavioral inhibition system; SD = standard deviation; SE = standard error; STAI = state trait anxiety inventory;